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Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.
Bártek J, Bártková J, Vojtĕsek B, Stasková Z, Lukás J, Rejthar A, Kovarík J, Midgley CA, Gannon JV, Lane DP. Bártek J, et al. Among authors: midgley ca. Oncogene. 1991 Sep;6(9):1699-703. Oncogene. 1991. PMID: 1923535
Archival analysis of p53 genetic and protein alterations in Chinese esophageal cancer.
Bennett WP, Hollstein MC, He A, Zhu SM, Resau JH, Trump BF, Metcalf RA, Welsh JA, Midgley C, Lane DP, et al. Bennett WP, et al. Oncogene. 1991 Oct;6(10):1779-84. Oncogene. 1991. PMID: 1923503
Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B.
Smart P, Lane EB, Lane DP, Midgley C, Vojtesek B, Laín S. Smart P, et al. Oncogene. 1999 Dec 2;18(51):7378-86. doi: 10.1038/sj.onc.1203260. Oncogene. 1999. PMID: 10602494
p53 protein alterations in human testicular cancer including pre-invasive intratubular germ-cell neoplasia.
Bártková J, Bártek J, Lukás J, Vojtĕsek B, Stasková Z, Rejthar A, Kovarík J, Midgley CA, Lane DP. Bártková J, et al. Among authors: midgley ca. Int J Cancer. 1991 Sep 9;49(2):196-202. doi: 10.1002/ijc.2910490209. Int J Cancer. 1991. PMID: 1652567
Xenopus p53 is biochemically similar to the human tumour suppressor protein p53 and is induced upon DNA damage in somatic cells.
Cox LS, Midgley CA, Lane DP. Cox LS, et al. Among authors: midgley ca. Oncogene. 1994 Oct;9(10):2951-9. Oncogene. 1994. PMID: 8084598
An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo.
Midgley CA, Desterro JM, Saville MK, Howard S, Sparks A, Hay RT, Lane DP. Midgley CA, et al. Oncogene. 2000 May 4;19(19):2312-23. doi: 10.1038/sj.onc.1203593. Oncogene. 2000. PMID: 10822382
p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.
Midgley CA, Lane DP. Midgley CA, et al. Oncogene. 1997 Sep 4;15(10):1179-89. doi: 10.1038/sj.onc.1201459. Oncogene. 1997. PMID: 9294611
The p53 response to ionising radiation in adult and developing murine tissues.
MacCallum DE, Hupp TR, Midgley CA, Stuart D, Campbell SJ, Harper A, Walsh FS, Wright EG, Balmain A, Lane DP, Hall PA. MacCallum DE, et al. Among authors: midgley ca. Oncogene. 1996 Dec 19;13(12):2575-87. Oncogene. 1996. PMID: 9000131
Epitope analysis of the murine p53 tumour suppressor protein.
Lane DP, Stephen CW, Midgley CA, Sparks A, Hupp TR, Daniels DA, Greaves R, Reid A, Vojtesek B, Picksley SM. Lane DP, et al. Among authors: midgley ca. Oncogene. 1996 Jun 6;12(11):2461-6. Oncogene. 1996. PMID: 8649788
Conformational changes in p53 analysed using new antibodies to the core DNA binding domain of the protein.
Vojtesek B, Dolezalova H, Lauerova L, Svitakova M, Havlis P, Kovarik J, Midgley CA, Lane DP. Vojtesek B, et al. Among authors: midgley ca. Oncogene. 1995 Jan 19;10(2):389-93. Oncogene. 1995. PMID: 7530828
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