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Discovery and characterization of 2-anilino-4- (thiazol-5-yl)pyrimidine transcriptional CDK inhibitors as anticancer agents.
Wang S, Griffiths G, Midgley CA, Barnett AL, Cooper M, Grabarek J, Ingram L, Jackson W, Kontopidis G, McClue SJ, McInnes C, McLachlan J, Meades C, Mezna M, Stuart I, Thomas MP, Zheleva DI, Lane DP, Jackson RC, Glover DM, Blake DG, Fischer PM. Wang S, et al. Among authors: midgley ca. Chem Biol. 2010 Oct 29;17(10):1111-21. doi: 10.1016/j.chembiol.2010.07.016. Chem Biol. 2010. PMID: 21035734
Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance.
McInnes C, Mazumdar A, Mezna M, Meades C, Midgley C, Scaerou F, Carpenter L, Mackenzie M, Taylor P, Walkinshaw M, Fischer PM, Glover D. McInnes C, et al. Nat Chem Biol. 2006 Nov;2(11):608-17. doi: 10.1038/nchembio825. Epub 2006 Oct 8. Nat Chem Biol. 2006. PMID: 17028581
Tumour suppressor genes and molecular chaperones.
Lane DP, Midgley C, Hupp T. Lane DP, et al. Philos Trans R Soc Lond B Biol Sci. 1993 Mar 29;339(1289):369-72; discussion 372-3. doi: 10.1098/rstb.1993.0036. Philos Trans R Soc Lond B Biol Sci. 1993. PMID: 8493291 Review.
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