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Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.
Nat Chem Biol. 2018 Feb;14(2):118-125. doi: 10.1038/nchembio.2528. Epub 2017 Dec 4.
Nat Chem Biol. 2018.
PMID: 29200206
Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.
O'Dowd CR, Helm MD, Rountree JSS, Flasz JT, Arkoudis E, Miel H, Hewitt PR, Jordan L, Barker O, Hughes C, Rozycka E, Cassidy E, McClelland K, Odrzywol E, Page N, Feutren-Burton S, Dvorkin S, Gavory G, Harrison T.
O'Dowd CR, et al. Among authors: miel h.
ACS Med Chem Lett. 2018 Feb 21;9(3):238-243. doi: 10.1021/acsmedchemlett.7b00512. eCollection 2018 Mar 8.
ACS Med Chem Lett. 2018.
PMID: 29541367
Free PMC article.
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Modern Organic Synthesis with α-Diazocarbonyl Compounds.
Ford A, Miel H, Ring A, Slattery CN, Maguire AR, McKervey MA.
Ford A, et al. Among authors: miel h.
Chem Rev. 2015 Sep 23;115(18):9981-10080. doi: 10.1021/acs.chemrev.5b00121. Epub 2015 Aug 18.
Chem Rev. 2015.
PMID: 26284754
Review.
No abstract available.
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Nonracemic 2-diazo-1-oxiranyl-ethanone, a versatile chiral epoxide educt in diazocarbonyl reactions.
Groarke M, McKervey MA, Miel H, Nieuwenhuyzen M.
Groarke M, et al. Among authors: miel h.
Org Lett. 2000 Aug 10;2(16):2393-5. doi: 10.1021/ol000034b.
Org Lett. 2000.
PMID: 10956504
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