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435 results
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Plants as bioreactors for biopharmaceuticals: regulatory considerations.
Miele L. Miele L. Trends Biotechnol. 1997 Feb;15(2):45-50. doi: 10.1016/S0167-7799(97)84202-3. Trends Biotechnol. 1997. PMID: 9081298 Review.
Toward the rational design of cell fate modifiers: notch signaling as a target for novel biopharmaceuticals.
Zlobin A, Jang M, Miele L. Zlobin A, et al. Among authors: miele l. Curr Pharm Biotechnol. 2000 Jul;1(1):83-106. doi: 10.2174/1389201003379013. Curr Pharm Biotechnol. 2000. PMID: 11467364 Review.
Stable, long-term bacterial production of soluble, dimeric, disulfide-bonded protein pharmaceuticals without antibiotic selection.
Mantile G, Fuchs C, Cordella-Miele E, Peri A, Mukherjee AB, Miele L. Mantile G, et al. Among authors: miele l. Biotechnol Prog. 2000 Jan-Feb;16(1):17-25. doi: 10.1021/bp990129g. Biotechnol Prog. 2000. PMID: 10662484
Antiflammins. Bioactive peptides derived from uteroglobin.
Miele L. Miele L. Ann N Y Acad Sci. 2000;923:128-40. doi: 10.1111/j.1749-6632.2000.tb05524.x. Ann N Y Acad Sci. 2000. PMID: 11193751 Review.
Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells.
Qin JZ, Ziffra J, Stennett L, Bodner B, Bonish BK, Chaturvedi V, Bennett F, Pollock PM, Trent JM, Hendrix MJ, Rizzo P, Miele L, Nickoloff BJ. Qin JZ, et al. Among authors: miele l. Cancer Res. 2005 Jul 15;65(14):6282-93. doi: 10.1158/0008-5472.CAN-05-0676. Cancer Res. 2005. PMID: 16024630
Off the beaten pathway: the complex cross talk between Notch and NF-kappaB.
Osipo C, Golde TE, Osborne BA, Miele LA. Osipo C, et al. Lab Invest. 2008 Jan;88(1):11-7. doi: 10.1038/labinvest.3700700. Epub 2007 Dec 3. Lab Invest. 2008. PMID: 18059366
Notch inhibitors for cancer treatment.
Espinoza I, Miele L. Espinoza I, et al. Among authors: miele l. Pharmacol Ther. 2013 Aug;139(2):95-110. doi: 10.1016/j.pharmthera.2013.02.003. Epub 2013 Feb 28. Pharmacol Ther. 2013. PMID: 23458608 Free PMC article. Review.
TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells.
Palaga T, Miele L, Golde TE, Osborne BA. Palaga T, et al. Among authors: miele l. J Immunol. 2003 Sep 15;171(6):3019-24. doi: 10.4049/jimmunol.171.6.3019. J Immunol. 2003. PMID: 12960327
Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells.
Curry CL, Reed LL, Golde TE, Miele L, Nickoloff BJ, Foreman KE. Curry CL, et al. Among authors: miele l. Oncogene. 2005 Sep 22;24(42):6333-44. doi: 10.1038/sj.onc.1208783. Oncogene. 2005. PMID: 15940249
Oxygen concentration determines the biological effects of NOTCH-1 signaling in adenocarcinoma of the lung.
Chen Y, De Marco MA, Graziani I, Gazdar AF, Strack PR, Miele L, Bocchetta M. Chen Y, et al. Among authors: miele l. Cancer Res. 2007 Sep 1;67(17):7954-9. doi: 10.1158/0008-5472.CAN-07-1229. Cancer Res. 2007. PMID: 17804701
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