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Off the beaten pathway: the complex cross talk between Notch and NF-kappaB.
Osipo C, Golde TE, Osborne BA, Miele LA. Osipo C, et al. Among authors: miele la. Lab Invest. 2008 Jan;88(1):11-7. doi: 10.1038/labinvest.3700700. Epub 2007 Dec 3. Lab Invest. 2008. PMID: 18059366
Arbiter of differentiation and death: Notch signaling meets apoptosis.
Miele L, Osborne B. Miele L, et al. J Cell Physiol. 1999 Dec;181(3):393-409. doi: 10.1002/(SICI)1097-4652(199912)181:3<393::AID-JCP3>3.0.CO;2-6. J Cell Physiol. 1999. PMID: 10528225 Review.
Notch signaling as a target in multimodality cancer therapy.
Jang MS, Zlobin A, Kast WM, Miele L. Jang MS, et al. Curr Opin Mol Ther. 2000 Feb;2(1):55-65. Curr Opin Mol Ther. 2000. PMID: 11249652 Review.
Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain.
Wang J, Shelly L, Miele L, Boykins R, Norcross MA, Guan E. Wang J, et al. J Immunol. 2001 Jul 1;167(1):289-95. doi: 10.4049/jimmunol.167.1.289. J Immunol. 2001. PMID: 11418662
Toward the rational design of cell fate modifiers: notch signaling as a target for novel biopharmaceuticals.
Zlobin A, Jang M, Miele L. Zlobin A, et al. Curr Pharm Biotechnol. 2000 Jul;1(1):83-106. doi: 10.2174/1389201003379013. Curr Pharm Biotechnol. 2000. PMID: 11467364 Review.
Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells.
Cheng P, Zlobin A, Volgina V, Gottipati S, Osborne B, Simel EJ, Miele L, Gabrilovich DI. Cheng P, et al. J Immunol. 2001 Oct 15;167(8):4458-67. doi: 10.4049/jimmunol.167.8.4458. J Immunol. 2001. PMID: 11591772
Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma.
Nickoloff BJ, Qin JZ, Chaturvedi V, Denning MF, Bonish B, Miele L. Nickoloff BJ, et al. Cell Death Differ. 2002 Aug;9(8):842-55. doi: 10.1038/sj.cdd.4401036. Cell Death Differ. 2002. PMID: 12107827
Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells.
Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, Osborne BA, Gottipati S, Aster JC, Hahn WC, Rudolf M, Siziopikou K, Kast WM, Miele L. Weijzen S, et al. Nat Med. 2002 Sep;8(9):979-86. doi: 10.1038/nm754. Epub 2002 Aug 19. Nat Med. 2002. PMID: 12185362
The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells.
Weijzen S, Velders MP, Elmishad AG, Bacon PE, Panella JR, Nickoloff BJ, Miele L, Kast WM. Weijzen S, et al. J Immunol. 2002 Oct 15;169(8):4273-8. doi: 10.4049/jimmunol.169.8.4273. J Immunol. 2002. PMID: 12370358
Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells.
Bocchetta M, Miele L, Pass HI, Carbone M. Bocchetta M, et al. Oncogene. 2003 Jan 9;22(1):81-9. doi: 10.1038/sj.onc.1206097. Oncogene. 2003. PMID: 12527910
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