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Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging.
Gambino V, De Michele G, Venezia O, Migliaccio P, Dall'Olio V, Bernard L, Minardi SP, Della Fazia MA, Bartoli D, Servillo G, Alcalay M, Luzi L, Giorgio M, Scrable H, Pelicci PG, Migliaccio E. Gambino V, et al. Among authors: migliaccio e. Aging Cell. 2013 Jun;12(3):435-45. doi: 10.1111/acel.12060. Epub 2013 Mar 27. Aging Cell. 2013. PMID: 23448364 Free PMC article.
p66Shc-generated oxidative signal promotes fat accumulation.
Berniakovich I, Trinei M, Stendardo M, Migliaccio E, Minucci S, Bernardi P, Pelicci PG, Giorgio M. Berniakovich I, et al. Among authors: migliaccio e. J Biol Chem. 2008 Dec 5;283(49):34283-93. doi: 10.1074/jbc.M804362200. Epub 2008 Oct 6. J Biol Chem. 2008. PMID: 18838380 Free PMC article.
The influence of Shc proteins on life span in mice.
Ramsey JJ, Tran D, Giorgio M, Griffey SM, Koehne A, Laing ST, Taylor SL, Kim K, Cortopassi GA, Lloyd KC, Hagopian K, Tomilov AA, Migliaccio E, Pelicci PG, McDonald RB. Ramsey JJ, et al. Among authors: migliaccio e. J Gerontol A Biol Sci Med Sci. 2014 Oct;69(10):1177-85. doi: 10.1093/gerona/glt198. Epub 2013 Dec 14. J Gerontol A Biol Sci Med Sci. 2014. PMID: 24336818 Free PMC article.
47 results