Milad M - Search Results

1

Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib.

Charles-Schoeman C, Fleischmann R, Davignon J, Schwartz H, Turner SM, Beysen C, Milad M, Hellerstein MK, Luo Z, Kaplan IV, Riese R, Zuckerman A, McInnes IB. Charles-Schoeman C, et al. Among authors: milad m. Arthritis Rheumatol. 2015 Mar;67(3):616-25. doi: 10.1002/art.38974. Arthritis Rheumatol. 2015. PMID: 25470338 Free PMC article. Clinical Trial.

2

Efficacy and safety of ETC-1002, a novel investigational low-density lipoprotein-cholesterol-lowering therapy for the treatment of patients with hypercholesterolemia and type 2 diabetes mellitus.

Gutierrez MJ, Rosenberg NL, Macdougall DE, Hanselman JC, Margulies JR, Strange P, Milad MA, McBride SJ, Newton RS. Gutierrez MJ, et al. Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):676-83. doi: 10.1161/ATVBAHA.113.302677. Epub 2014 Jan 2. Arterioscler Thromb Vasc Biol. 2014. PMID: 24385236 Clinical Trial.

3

Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor.

Sahi J, Milad MA, Zheng X, Rose KA, Wang H, Stilgenbauer L, Gilbert D, Jolley S, Stern RH, LeCluyse EL. Sahi J, et al. J Pharmacol Exp Ther. 2003 Sep;306(3):1027-34. doi: 10.1124/jpet.103.050526. Epub 2003 May 23. J Pharmacol Exp Ther. 2003. PMID: 12766253

4

Udp-glucuronosyltransferase 2b7 is the major enzyme responsible for gemcabene glucuronidation in human liver microsomes.

Bauman JN, Goosen TC, Tugnait M, Peterkin V, Hurst SI, Menning LC, Milad M, Court MH, Williams JA. Bauman JN, et al. Among authors: milad m. Drug Metab Dispos. 2005 Sep;33(9):1349-54. doi: 10.1124/dmd.105.005108. Epub 2005 Jun 24. Drug Metab Dispos. 2005. PMID: 15980101

5

Preclinical safety evaluation of avasimibe in beagle dogs: an ACAT inhibitor with minimal adrenal effects.

Robertson DG, Breider MA, Milad MA. Robertson DG, et al. Among authors: milad ma. Toxicol Sci. 2001 Feb;59(2):324-34. doi: 10.1093/toxsci/59.2.324. Toxicol Sci. 2001. PMID: 11158726

6

An association study of 43 SNPs in 16 candidate genes with atorvastatin response.

Thompson JF, Man M, Johnson KJ, Wood LS, Lira ME, Lloyd DB, Banerjee P, Milos PM, Myrand SP, Paulauskis J, Milad MA, Sasiela WJ. Thompson JF, et al. Among authors: milad ma. Pharmacogenomics J. 2005;5(6):352-8. doi: 10.1038/sj.tpj.6500328. Pharmacogenomics J. 2005. PMID: 16103896 Clinical Trial.

7

Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.

Pfefferkorn JA, Litchfield J, Hutchings R, Cheng XM, Larsen SD, Auerbach B, Bush MR, Lee C, Erasga N, Bowles DM, Boyles DC, Lu G, Sekerke C, Askew V, Hanselman JC, Dillon L, Lin Z, Robertson A, Olsen K, Boustany C, Atkinson K, Goosen TC, Sahasrabudhe V, Chupka J, Duignan DB, Feng B, Scialis R, Kimoto E, Bi YA, Lai Y, El-Kattan A, Bakker-Arkema R, Barclay P, Kindt E, Le V, Mandema JW, Milad M, Tait BD, Kennedy R, Trivedi BK, Kowala M. Pfefferkorn JA, et al. Among authors: milad m. Bioorg Med Chem Lett. 2011 May 1;21(9):2725-31. doi: 10.1016/j.bmcl.2010.11.103. Epub 2010 Nov 26. Bioorg Med Chem Lett. 2011. PMID: 21183342

8

Evaluation of Maternal Drug Exposure Following the Administration of Antenatal Corticosteroids During Late Pregnancy Using Physiologically-Based Pharmacokinetic Modeling.

Ke AB, Milad MA. Ke AB, et al. Clin Pharmacol Ther. 2019 Jul;106(1):164-173. doi: 10.1002/cpt.1438. Epub 2019 May 6. Clin Pharmacol Ther. 2019. PMID: 30924921

9

Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo.

Sahi J, Stern RH, Milad MA, Rose KA, Gibson G, Zheng X, Stilgenbauer L, Sadagopan N, Jolley S, Gilbert D, LeCluyse EL. Sahi J, et al. Drug Metab Dispos. 2004 Dec;32(12):1370-6. doi: 10.1124/dmd.104.000208. Epub 2004 Aug 27. Drug Metab Dispos. 2004. PMID: 15333513

10

Temporally and anatomically specific contributions of the human amygdala to threat and safety learning.

Wen Z, Raio CM, Pace-Schott EF, Lazar SW, LeDoux JE, Phelps EA, Milad MR. Wen Z, et al. Among authors: milad mr. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2204066119. doi: 10.1073/pnas.2204066119. Epub 2022 Jun 21. Proc Natl Acad Sci U S A. 2022. PMID: 35727981 Free article.

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