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17-a-estradiol late in life extends lifespan in aging UM-HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex.
Harrison DE, Strong R, Reifsnyder P, Kumar N, Fernandez E, Flurkey K, Javors MA, Lopez-Cruzan M, Macchiarini F, Nelson JF, Bitto A, Sindler AL, Cortopassi G, Kavanagh K, Leng L, Bucala R, Rosenthal N, Salmon A, Stearns TM, Bogue M, Miller RA. Harrison DE, et al. Among authors: miller ra. Aging Cell. 2021 Mar 31:e13328. doi: 10.1111/acel.13328. Online ahead of print. Aging Cell. 2021. PMID: 33788371 Free article.
CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses.
Russell RM, Bibollet-Ruche F, Liu W, Sherrill-Mix S, Li Y, Connell J, Loy DE, Trimboli S, Smith AG, Avitto AN, Gondim MVP, Plenderleith LJ, Wetzel KS, Collman RG, Ayouba A, Esteban A, Peeters M, Kohler WJ, Miller RA, François-Souquiere S, Switzer WM, Hirsch VM, Marx PA, Piel AK, Stewart FA, Georgiev AV, Sommer V, Bertolani P, Hart JA, Hart TB, Shaw GM, Sharp PM, Hahn BH. Russell RM, et al. Among authors: miller ra. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2025914118. doi: 10.1073/pnas.2025914118. Proc Natl Acad Sci U S A. 2021. PMID: 33771926 Free PMC article.
Rapamycin-mediated mouse lifespan extension: Late-life dosage regimes with sex-specific effects.
Strong R, Miller RA, Bogue M, Fernandez E, Javors MA, Libert S, Marinez PA, Murphy MP, Musi N, Nelson JF, Petrascheck M, Reifsnyder P, Richardson A, Salmon AB, Macchiarini F, Harrison DE. Strong R, et al. Among authors: miller ra. Aging Cell. 2020 Nov;19(11):e13269. doi: 10.1111/acel.13269. Epub 2020 Nov 4. Aging Cell. 2020. PMID: 33145977 Free PMC article.
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