Miller RE - Search Results

1

P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme.

Dolle RE, Hoyer D, Prasad CV, Schmidt SJ, Helaszek CT, Miller RE, Ator MA. Dolle RE, et al. Among authors: miller re. J Med Chem. 1994 Mar 4;37(5):563-4. doi: 10.1021/jm00031a003. J Med Chem. 1994. PMID: 8126694 No abstract available.

2

Aspartyl alpha-((diphenylphosphinyl)oxy)methyl ketones as novel inhibitors of interleukin-1 beta converting enzyme. Utility of the diphenylphosphinic acid leaving group for the inhibition of cysteine proteases.

Dolle RE, Singh J, Whipple D, Osifo IK, Speier G, Graybill TL, Gregory JS, Harris AL, Helaszek CT, Miller RE, et al. Dolle RE, et al. Among authors: miller re. J Med Chem. 1995 Jan 20;38(2):220-2. doi: 10.1021/jm00002a002. J Med Chem. 1995. PMID: 7830263 No abstract available.

3

Aspartyl alpha-((1-phenyl-3-(trifluoromethyl)-pyrazol-5-yl)oxy)methyl ketones as interleukin-1 beta converting enzyme inhibitors. Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding.

Dolle RE, Singh J, Rinker J, Hoyer D, Prasad CV, Graybill TL, Salvino JM, Helaszek CT, Miller RE, Ator MA. Dolle RE, et al. Among authors: miller re. J Med Chem. 1994 Nov 11;37(23):3863-6. doi: 10.1021/jm00049a001. J Med Chem. 1994. PMID: 7966144 No abstract available.

4

Preparation and evaluation of peptidic aspartyl hemiacetals as reversible inhibitors of interleukin-1 beta converting enzyme (ICE).

Graybill TL, Dolle RE, Helaszek CT, Miller RE, Ator MA. Graybill TL, et al. Among authors: miller re. Int J Pept Protein Res. 1994 Aug;44(2):173-82. doi: 10.1111/j.1399-3011.1994.tb00573.x. Int J Pept Protein Res. 1994. PMID: 7982761

5

Secretion of human monocyte mature IL-1 beta: optimization of culture conditions and inhibition by ICE inhibitors.

Uhl J, Krasney P, Brophy L, Arnold R, Dolle R, Helaszek C, Miller R, Gilman S, Ator M. Uhl J, et al. Inflamm Res. 1995 Aug;44 Suppl 2:S211-2. doi: 10.1007/BF01778338. Inflamm Res. 1995. PMID: 8548404 No abstract available.

6

Inhibition of mature IL-1 beta production in murine macrophages and a murine model of inflammation by WIN 67694, an inhibitor of IL-1 beta converting enzyme.

Miller BE, Krasney PA, Gauvin DM, Holbrook KB, Koonz DJ, Abruzzese RV, Miller RE, Pagani KA, Dolle RE, Ator MA, et al. Miller BE, et al. Among authors: miller re. J Immunol. 1995 Feb 1;154(3):1331-8. J Immunol. 1995. PMID: 7822802

7

Structure-activity relationships of the antimalarial agent artemisinin. 3. Total synthesis of (+)-13-carbaartemisinin and related tetra- and tricyclic structures.

Avery MA, Fan P, Karle JM, Bonk JD, Miller R, Goins DK. Avery MA, et al. J Med Chem. 1996 Apr 26;39(9):1885-97. doi: 10.1021/jm950921y. J Med Chem. 1996. PMID: 8627612

8

Structure-activity relationships of the antimalarial agent artemisinin. 2. Effect of heteroatom substitution at O-11: synthesis and bioassay of N-alkyl-11-aza-9-desmethylartemisinins.

Avery MA, Bonk JD, Chong WK, Mehrotra S, Miller R, Milhous W, Goins DK, Venkatesan S, Wyandt C, Khan I, et al. Avery MA, et al. J Med Chem. 1995 Dec 22;38(26):5038-44. doi: 10.1021/jm00026a011. J Med Chem. 1995. PMID: 8544180

9

Structure-activity relationships of the antimalarial agent artemisinin. 4. Effect of substitution at C-3.

Avery MA, Mehrotra S, Bonk JD, Vroman JA, Goins DK, Miller R. Avery MA, et al. J Med Chem. 1996 Jul 19;39(15):2900-6. doi: 10.1021/jm960200e. J Med Chem. 1996. PMID: 8709124

10

In vitro antimalarial activity of chalcones and their derivatives.

Li R, Kenyon GL, Cohen FE, Chen X, Gong B, Dominguez JN, Davidson E, Kurzban G, Miller RE, Nuzum EO, et al. Li R, et al. Among authors: miller re. J Med Chem. 1995 Dec 22;38(26):5031-7. doi: 10.1021/jm00026a010. J Med Chem. 1995. PMID: 8544179

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