Miller SM - Search Results

1

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.

Hu JH, Miller SM, Geurts MH, Tang W, Chen L, Sun N, Zeina CM, Gao X, Rees HA, Lin Z, Liu DR. Hu JH, et al. Among authors: miller sm. Nature. 2018 Apr 5;556(7699):57-63. doi: 10.1038/nature26155. Epub 2018 Feb 28. Nature. 2018. PMID: 29512652 Free PMC article.

2

Targeting fidelity of adenine and cytosine base editors in mouse embryos.

Lee HK, Willi M, Miller SM, Kim S, Liu C, Liu DR, Hennighausen L. Lee HK, et al. Among authors: miller sm. Nat Commun. 2018 Nov 15;9(1):4804. doi: 10.1038/s41467-018-07322-7. Nat Commun. 2018. PMID: 30442934 Free PMC article.

3

Simultaneous targeting of linked loci in mouse embryos using base editing.

Lee HK, Willi M, Smith HE, Miller SM, Liu DR, Liu C, Hennighausen L. Lee HK, et al. Among authors: miller sm. Sci Rep. 2019 Feb 7;9(1):1662. doi: 10.1038/s41598-018-33533-5. Sci Rep. 2019. PMID: 30733567 Free PMC article.

4

Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.

Huang TP, Zhao KT, Miller SM, Gaudelli NM, Oakes BL, Fellmann C, Savage DF, Liu DR. Huang TP, et al. Among authors: miller sm. Nat Biotechnol. 2019 Jun;37(6):626-631. doi: 10.1038/s41587-019-0134-y. Epub 2019 May 20. Nat Biotechnol. 2019. PMID: 31110355 Free PMC article.

5

Author Correction: Circularly permuted and PAM-modified Cas9 variants broaden the targeting scope of base editors.

Huang TP, Zhao KT, Miller SM, Gaudelli NM, Oakes BL, Fellmann C, Savage DF, Liu DR. Huang TP, et al. Among authors: miller sm. Nat Biotechnol. 2019 Jul;37(7):820. doi: 10.1038/s41587-019-0168-1. Nat Biotechnol. 2019. PMID: 31182863

6

Continuous evolution of SpCas9 variants compatible with non-G PAMs.

Miller SM, Wang T, Randolph PB, Arbab M, Shen MW, Huang TP, Matuszek Z, Newby GA, Rees HA, Liu DR. Miller SM, et al. Nat Biotechnol. 2020 Apr;38(4):471-481. doi: 10.1038/s41587-020-0412-8. Epub 2020 Feb 10. Nat Biotechnol. 2020. PMID: 32042170 Free PMC article.

7

Phage-assisted continuous and non-continuous evolution.

Miller SM, Wang T, Liu DR. Miller SM, et al. Nat Protoc. 2020 Dec;15(12):4101-4127. doi: 10.1038/s41596-020-00410-3. Epub 2020 Nov 16. Nat Protoc. 2020. PMID: 33199872 Free PMC article.

8

Base editing of haematopoietic stem cells rescues sickle cell disease in mice.

Newby GA, Yen JS, Woodard KJ, Mayuranathan T, Lazzarotto CR, Li Y, Sheppard-Tillman H, Porter SN, Yao Y, Mayberry K, Everette KA, Jang Y, Podracky CJ, Thaman E, Lechauve C, Sharma A, Henderson JM, Richter MF, Zhao KT, Miller SM, Wang T, Koblan LW, McCaffrey AP, Tisdale JF, Kalfa TA, Pruett-Miller SM, Tsai SQ, Weiss MJ, Liu DR. Newby GA, et al. Among authors: miller sm. Nature. 2021 Jul;595(7866):295-302. doi: 10.1038/s41586-021-03609-w. Epub 2021 Jun 2. Nature. 2021. PMID: 34079130 Free PMC article.

9

High-throughput continuous evolution of compact Cas9 variants targeting single-nucleotide-pyrimidine PAMs.

Huang TP, Heins ZJ, Miller SM, Wong BG, Balivada PA, Wang T, Khalil AS, Liu DR. Huang TP, et al. Among authors: miller sm. Nat Biotechnol. 2023 Jan;41(1):96-107. doi: 10.1038/s41587-022-01410-2. Epub 2022 Sep 8. Nat Biotechnol. 2023. PMID: 36076084 Free PMC article.

10

A manganese catalyst for highly reactive yet chemoselective intramolecular C(sp(3))-H amination.

Paradine SM, Griffin JR, Zhao J, Petronico AL, Miller SM, Christina White M. Paradine SM, et al. Among authors: miller sm. Nat Chem. 2015 Dec;7(12):987-94. doi: 10.1038/nchem.2366. Epub 2015 Oct 5. Nat Chem. 2015. PMID: 26587714 Free PMC article.

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