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Concurrent down-regulation of IP prostanoid receptors and the alpha-subunit of the stimulatory guanine-nucleotide-binding protein (Gs) during prolonged exposure of neuroblastoma x glioma cells to prostanoid agonists. Quantification and functional implications.
Adie EJ, Mullaney I, McKenzie FR, Milligan G. Adie EJ, et al. Among authors: milligan g. Biochem J. 1992 Jul 15;285 ( Pt 2)(Pt 2):529-36. doi: 10.1042/bj2850529. Biochem J. 1992. PMID: 1379045 Free PMC article.
The remaining receptors were capable of interacting with the stimulatory G-protein (Gs) of the adenylate cyclase cascade, as saturation analysis of the binding of [3H]PGE1 indicated that they had a similar affinity for the 3H-labelled ligand, and because the specific bindi …
The remaining receptors were capable of interacting with the stimulatory G-protein (Gs) of the adenylate cyclase cascade, as saturati …
775 results