Mills JH - Search Results

1

Structural Insights into How Protein Environments Tune the Spectroscopic Properties of a Noncanonical Amino Acid Fluorophore.

Henderson JN, Simmons CR, Fahmi NE, Jeffs JW, Borges CR, Mills JH. Henderson JN, et al. Among authors: mills jh. Biochemistry. 2020 Sep 22;59(37):3401-3410. doi: 10.1021/acs.biochem.0c00474. Epub 2020 Sep 3. Biochemistry. 2020. PMID: 32845612 Free PMC article.

2

An intrinsic FRET sensor of protein-ligand interactions.

Gleason PR, Kelly PI, Grisingher DW, Mills JH. Gleason PR, et al. Among authors: mills jh. Org Biomol Chem. 2020 Jun 7;18(21):4079-4084. doi: 10.1039/d0ob00793e. Epub 2020 May 19. Org Biomol Chem. 2020. PMID: 32427252 Free PMC article.

3

Structural Origins of Altered Spectroscopic Properties upon Ligand Binding in Proteins Containing a Fluorescent Noncanonical Amino Acid.

Gleason PR, Kolbaba-Kartchner B, Henderson JN, Stahl EP, Simmons CR, Mills JH. Gleason PR, et al. Among authors: mills jh. Biochemistry. 2021 Aug 31;60(34):2577-2585. doi: 10.1021/acs.biochem.1c00291. Epub 2021 Aug 20. Biochemistry. 2021. PMID: 34415744 Free PMC article.

4

Structural Basis for Blocked Excited State Proton Transfer in a Fluorescent, Photoacidic Non-Canonical Amino Acid-Containing Antibody Fragment.

Henderson JN, Simmons CR, Mills JH. Henderson JN, et al. Among authors: mills jh. J Mol Biol. 2022 Apr 30;434(8):167455. doi: 10.1016/j.jmb.2022.167455. Epub 2022 Jan 13. J Mol Biol. 2022. PMID: 35033559 Free PMC article.

5

Structural Characterization of Fluorescent Proteins Using Tunable Femtosecond Stimulated Raman Spectroscopy.

Chen C, Henderson JN, Ruchkin DA, Kirsh JM, Baranov MS, Bogdanov AM, Mills JH, Boxer SG, Fang C. Chen C, et al. Among authors: mills jh. Int J Mol Sci. 2023 Jul 26;24(15):11991. doi: 10.3390/ijms241511991. Int J Mol Sci. 2023. PMID: 37569365 Free PMC article.

6

Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy.

Mills JH, Khare SD, Bolduc JM, Forouhar F, Mulligan VK, Lew S, Seetharaman J, Tong L, Stoddard BL, Baker D. Mills JH, et al. J Am Chem Soc. 2013 Sep 11;135(36):13393-9. doi: 10.1021/ja403503m. Epub 2013 Aug 29. J Am Chem Soc. 2013. PMID: 23924187 Free PMC article.

7

Computational design of a homotrimeric metalloprotein with a trisbipyridyl core.

Mills JH, Sheffler W, Ener ME, Almhjell PJ, Oberdorfer G, Pereira JH, Parmeggiani F, Sankaran B, Zwart PH, Baker D. Mills JH, et al. Proc Natl Acad Sci U S A. 2016 Dec 27;113(52):15012-15017. doi: 10.1073/pnas.1600188113. Epub 2016 Dec 8. Proc Natl Acad Sci U S A. 2016. PMID: 27940918 Free PMC article.

8

Metal-chelating non-canonical amino acids in metalloprotein engineering and design.

Almhjell PJ, Mills JH. Almhjell PJ, et al. Among authors: mills jh. Curr Opin Struct Biol. 2018 Aug;51:170-176. doi: 10.1016/j.sbi.2018.06.001. Epub 2018 Jul 3. Curr Opin Struct Biol. 2018. PMID: 29980106 Review.

9

A General Strategy for Engineering Noncanonical Amino Acid Dependent Bacterial Growth.

Koh M, Yao A, Gleason PR, Mills JH, Schultz PG. Koh M, et al. Among authors: mills jh. J Am Chem Soc. 2019 Oct 16;141(41):16213-16216. doi: 10.1021/jacs.9b08491. Epub 2019 Oct 4. J Am Chem Soc. 2019. PMID: 31580059 Free PMC article.

10

The Role of Rigid Residues in Modulating TEM-1 β-Lactamase Function and Thermostability.

Kolbaba-Kartchner B, Kazan IC, Mills JH, Ozkan SB. Kolbaba-Kartchner B, et al. Among authors: mills jh. Int J Mol Sci. 2021 Mar 12;22(6):2895. doi: 10.3390/ijms22062895. Int J Mol Sci. 2021. PMID: 33809335 Free PMC article.

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