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Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease.
Milner JD, Ward JM, Keane-Myers A, Paul WE. Milner JD, et al. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):576-81. doi: 10.1073/pnas.0610289104. Epub 2007 Jan 3. Proc Natl Acad Sci U S A. 2007. PMID: 17202252 Free PMC article.
Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome.
Milner JD, Brenchley JM, Laurence A, Freeman AF, Hill BJ, Elias KM, Kanno Y, Spalding C, Elloumi HZ, Paulson ML, Davis J, Hsu A, Asher AI, O'Shea J, Holland SM, Paul WE, Douek DC. Milner JD, et al. Nature. 2008 Apr 10;452(7188):773-6. doi: 10.1038/nature06764. Epub 2008 Mar 12. Nature. 2008. PMID: 18337720 Free PMC article.
Hypomorphic Rag mutations can cause destructive midline granulomatous disease.
De Ravin SS, Cowen EW, Zarember KA, Whiting-Theobald NL, Kuhns DB, Sandler NG, Douek DC, Pittaluga S, Poliani PL, Lee YN, Notarangelo LD, Wang L, Alt FW, Kang EM, Milner JD, Niemela JE, Fontana-Penn M, Sinal SH, Malech HL. De Ravin SS, et al. Blood. 2010 Aug 26;116(8):1263-71. doi: 10.1182/blood-2010-02-267583. Epub 2010 May 20. Blood. 2010. PMID: 20489056 Free PMC article.
Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections.
Milner JD, Sandler NG, Douek DC. Milner JD, et al. Curr Opin HIV AIDS. 2010 Mar;5(2):179-83. doi: 10.1097/COH.0b013e328335ed3e. Curr Opin HIV AIDS. 2010. PMID: 20543597 Free PMC article. Review.
Altered T-cell receptor signaling in the pathogenesis of allergic disease.
Datta S, Milner JD. Datta S, et al. J Allergy Clin Immunol. 2011 Feb;127(2):351-4. doi: 10.1016/j.jaci.2010.11.033. J Allergy Clin Immunol. 2011. PMID: 21281865 Free PMC article. Review.
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