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Stimulation of nuclear sphingosine kinase activity by platelet-derived growth factor.
Kleuser B, Maceyka M, Milstien S, Spiegel S. Kleuser B, et al. Among authors: milstien s. FEBS Lett. 2001 Aug 10;503(1):85-90. doi: 10.1016/s0014-5793(01)02697-7. FEBS Lett. 2001. PMID: 11513860
Platelet-derived growth factor, in addition to rapidly stimulating cytosolic sphingosine kinase, also induced a large increase in nucleoplasm-associated activity after 12-24 h that correlated with progression of cells to the S-phase of the cell cycle and translocation of s …
Platelet-derived growth factor, in addition to rapidly stimulating cytosolic sphingosine kinase, also induced a large increase in nucleoplas …
Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide.
Giussani P, Maceyka M, Le Stunff H, Mikami A, Lépine S, Wang E, Kelly S, Merrill AH Jr, Milstien S, Spiegel S. Giussani P, et al. Among authors: milstien s. Mol Cell Biol. 2006 Jul;26(13):5055-69. doi: 10.1128/MCB.02107-05. Mol Cell Biol. 2006. PMID: 16782891 Free PMC article.
This was not due to inhibition of ceramide metabolism to sphingomyelin or monohexosylceramides but rather to the inhibition of ER-to-Golgi trafficking, determined with the fluorescent ceramide analog N-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-pentanoyl)-d …
This was not due to inhibition of ceramide metabolism to sphingomyelin or monohexosylceramides but rather to the inhibition of ER-to-Golgi t …
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
Maceyka M, Milstien S, Spiegel S. Maceyka M, et al. Among authors: milstien s. FEBS J. 2013 Dec;280(24):6367-72. doi: 10.1111/febs.12505. Epub 2013 Sep 23. FEBS J. 2013. PMID: 23992240 Free PMC article. Review.
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer.
Nagahashi M, Hait NC, Maceyka M, Avni D, Takabe K, Milstien S, Spiegel S. Nagahashi M, et al. Among authors: milstien s. Adv Biol Regul. 2014 Jan;54:112-20. doi: 10.1016/j.jbior.2013.10.001. Epub 2013 Oct 16. Adv Biol Regul. 2014. PMID: 24210073 Free PMC article. Review.
Functions of the multifaceted family of sphingosine kinases and some close relatives.
Spiegel S, Milstien S. Spiegel S, et al. Among authors: milstien s. J Biol Chem. 2007 Jan 26;282(4):2125-9. doi: 10.1074/jbc.R600028200. Epub 2006 Nov 29. J Biol Chem. 2007. PMID: 17135245 Review. No abstract available.
Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases.
Hait NC, Oskeritzian CA, Paugh SW, Milstien S, Spiegel S. Hait NC, et al. Among authors: milstien s. Biochim Biophys Acta. 2006 Dec;1758(12):2016-26. doi: 10.1016/j.bbamem.2006.08.007. Epub 2006 Aug 18. Biochim Biophys Acta. 2006. PMID: 16996023 Review.
Sphingosine kinase 1 is required for migration, proliferation and survival of MCF-7 human breast cancer cells.
Sarkar S, Maceyka M, Hait NC, Paugh SW, Sankala H, Milstien S, Spiegel S. Sarkar S, et al. Among authors: milstien s. FEBS Lett. 2005 Oct 10;579(24):5313-7. doi: 10.1016/j.febslet.2005.08.055. FEBS Lett. 2005. PMID: 16194537
Aminoacylase 1 is a sphingosine kinase 1-interacting protein.
Maceyka M, Nava VE, Milstien S, Spiegel S. Maceyka M, et al. Among authors: milstien s. FEBS Lett. 2004 Jun 18;568(1-3):30-4. doi: 10.1016/j.febslet.2004.04.093. FEBS Lett. 2004. PMID: 15196915
Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis.
Le Stunff H, Mikami A, Giussani P, Hobson JP, Jolly PS, Milstien S, Spiegel S. Le Stunff H, et al. Among authors: milstien s. J Biol Chem. 2004 Aug 13;279(33):34290-7. doi: 10.1074/jbc.M404907200. Epub 2004 Jun 4. J Biol Chem. 2004. PMID: 15180992
The immunosuppressant FTY720 is phosphorylated by sphingosine kinase type 2.
Paugh SW, Payne SG, Barbour SE, Milstien S, Spiegel S. Paugh SW, et al. Among authors: milstien s. FEBS Lett. 2003 Nov 6;554(1-2):189-93. doi: 10.1016/s0014-5793(03)01168-2. FEBS Lett. 2003. PMID: 14596938
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