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Targeting monocyte chemoattractant protein-1 signalling in disease.
Dawson J, Miltz W, Mir AK, Wiessner C. Dawson J, et al. Among authors: miltz w. Expert Opin Ther Targets. 2003 Feb;7(1):35-48. doi: 10.1517/14728222.7.1.35. Expert Opin Ther Targets. 2003. PMID: 12556201 Review.
Design and synthesis of potent and orally active GPR4 antagonists with modulatory effects on nociception, inflammation, and angiogenesis.
Miltz W, Velcicky J, Dawson J, Littlewood-Evans A, Ludwig MG, Seuwen K, Feifel R, Oberhauser B, Meyer A, Gabriel D, Nash M, Loetscher P. Miltz W, et al. Bioorg Med Chem. 2017 Aug 15;25(16):4512-4525. doi: 10.1016/j.bmc.2017.06.050. Epub 2017 Jun 29. Bioorg Med Chem. 2017. PMID: 28689977
Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.
Numao S, Hasler F, Laguerre C, Srinivas H, Wack N, Jäger P, Schmid A, Osmont A, Röthlisberger P, Houguenade J, Bergsdorf C, Dawson J, Carte N, Hofmann A, Markert C, Hardaker L, Billich A, Wolf RM, Penno CA, Bollbuck B, Miltz W, Röhn TA. Numao S, et al. Among authors: miltz w. Sci Rep. 2017 Oct 19;7(1):13591. doi: 10.1038/s41598-017-13490-1. Sci Rep. 2017. PMID: 29051536 Free PMC article.
Development of Selective, Orally Active GPR4 Antagonists with Modulatory Effects on Nociception, Inflammation, and Angiogenesis.
Velcicky J, Miltz W, Oberhauser B, Orain D, Vaupel A, Weigand K, Dawson King J, Littlewood-Evans A, Nash M, Feifel R, Loetscher P. Velcicky J, et al. Among authors: miltz w. J Med Chem. 2017 May 11;60(9):3672-3683. doi: 10.1021/acs.jmedchem.6b01703. Epub 2017 Apr 26. J Med Chem. 2017. PMID: 28445047
A cassette-dosing approach for improvement of oral bioavailability of dual TACE/MMP inhibitors.
Janser P, Neumann U, Miltz W, Feifel R, Buhl T. Janser P, et al. Among authors: miltz w. Bioorg Med Chem Lett. 2006 May 15;16(10):2632-6. doi: 10.1016/j.bmcl.2006.02.042. Epub 2006 Mar 3. Bioorg Med Chem Lett. 2006. PMID: 16516469
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