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Fibulin-5/DANCE is essential for elastogenesis in vivo.
Nakamura T, Lozano PR, Ikeda Y, Iwanaga Y, Hinek A, Minamisawa S, Cheng CF, Kobuke K, Dalton N, Takada Y, Tashiro K, Ross J Jr, Honjo T, Chien KR. Nakamura T, et al. Among authors: minamisawa s. Nature. 2002 Jan 10;415(6868):171-5. doi: 10.1038/415171a. Nature. 2002. PMID: 11805835
ErbB2 is essential in the prevention of dilated cardiomyopathy.
Crone SA, Zhao YY, Fan L, Gu Y, Minamisawa S, Liu Y, Peterson KL, Chen J, Kahn R, Condorelli G, Ross J Jr, Chien KR, Lee KF. Crone SA, et al. Among authors: minamisawa s. Nat Med. 2002 May;8(5):459-65. doi: 10.1038/nm0502-459. Nat Med. 2002. PMID: 11984589
A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages.
Nguyên-Trân VT, Kubalak SW, Minamisawa S, Fiset C, Wollert KC, Brown AB, Ruiz-Lozano P, Barrere-Lemaire S, Kondo R, Norman LW, Gourdie RG, Rahme MM, Feld GK, Clark RB, Giles WR, Chien KR. Nguyên-Trân VT, et al. Among authors: minamisawa s. Cell. 2000 Sep 1;102(5):671-82. doi: 10.1016/s0092-8674(00)00089-1. Cell. 2000. PMID: 11007485
A post-transcriptional compensatory pathway in heterozygous ventricular myosin light chain 2-deficient mice results in lack of gene dosage effect during normal cardiac growth or hypertrophy.
Minamisawa S, Gu Y, Ross J Jr, Chien KR, Chen J. Minamisawa S, et al. J Biol Chem. 1999 Apr 9;274(15):10066-70. doi: 10.1074/jbc.274.15.10066. J Biol Chem. 1999. PMID: 10187786
Our previous study of homozygous mutants of the ventricular specific isoform of myosin light chain 2 (mlc-2v) demonstrated that mlc-2v plays an essential role in murine heart development (Chen, J., Kubalak, S. W., Minamisawa, S., Price, R. L., Becker, K. D., …
Our previous study of homozygous mutants of the ventricular specific isoform of myosin light chain 2 (mlc-2v) demonstrated that mlc-2v plays …
Tissue thrombin is associated with the pathogenesis of dilated cardiomyopathy.
Ito K, Hongo K, Date T, Ikegami M, Hano H, Owada M, Morimoto S, Kashiwagi Y, Katoh D, Yoshino T, Yoshii A, Kimura H, Nagoshi T, Kajimura I, Kusakari Y, Akaike T, Minamisawa S, Ogawa K, Minai K, Ogawa T, Kawai M, Yajima J, Matsuo S, Yamane T, Taniguchi I, Morimoto S, Yoshimura M. Ito K, et al. Among authors: minamisawa s. Int J Cardiol. 2017 Feb 1;228:821-827. doi: 10.1016/j.ijcard.2016.11.176. Epub 2016 Nov 9. Int J Cardiol. 2017. PMID: 27888761
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