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Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.
Scozzafava A, Menabuoni L, Mincione F, Supuran CT. Scozzafava A, et al. Among authors: mincione f. J Med Chem. 2002 Mar 28;45(7):1466-76. doi: 10.1021/jm0108202. J Med Chem. 2002. PMID: 11906288
A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology.
Fabrizi F, Mincione F, Somma T, Scozzafava G, Galassi F, Masini E, Impagnatiello F, Supuran CT. Fabrizi F, et al. Among authors: mincione f. J Enzyme Inhib Med Chem. 2012 Feb;27(1):138-47. doi: 10.3109/14756366.2011.597749. Epub 2011 Aug 4. J Enzyme Inhib Med Chem. 2012. PMID: 21815773
Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action.
Mincione F, Benedini F, Biondi S, Cecchi A, Temperini C, Formicola G, Pacileo I, Scozzafava A, Masini E, Supuran CT. Mincione F, et al. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3216-21. doi: 10.1016/j.bmcl.2011.04.046. Epub 2011 Apr 20. Bioorg Med Chem Lett. 2011. PMID: 21549597
The development of topically acting carbonic anhydrase inhibitors as antiglaucoma agents.
Mincione F, Scozzafava A, Supuran CT. Mincione F, et al. Curr Pharm Des. 2008;14(7):649-54. doi: 10.2174/138161208783877866. Curr Pharm Des. 2008. PMID: 18336310 Review.
The development of topically acting carbonic anhydrase inhibitors as anti-glaucoma agents.
Mincione F, Scozzafava A, Supuran CT. Mincione F, et al. Curr Top Med Chem. 2007;7(9):849-54. doi: 10.2174/156802607780636735. Curr Top Med Chem. 2007. PMID: 17504129 Review.
Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.
Mincione F, Starnotti M, Masini E, Bacciottini L, Scrivanti C, Casini A, Vullo D, Scozzafava A, Supuran CT. Mincione F, et al. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3821-7. doi: 10.1016/j.bmcl.2005.06.054. Bioorg Med Chem Lett. 2005. PMID: 16039853
Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity.
de Leval X, Ilies M, Casini A, Dogné JM, Scozzafava A, Masini E, Mincione F, Starnotti M, Supuran CT. de Leval X, et al. Among authors: mincione f. J Med Chem. 2004 May 20;47(11):2796-804. doi: 10.1021/jm031116j. J Med Chem. 2004. PMID: 15139757
Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits.
Winum JY, Casini A, Mincione F, Starnotti M, Montero JL, Scozzafava A, Supuran CT. Winum JY, et al. Among authors: mincione f. Bioorg Med Chem Lett. 2004 Jan 5;14(1):225-9. doi: 10.1016/j.bmcl.2003.09.063. Bioorg Med Chem Lett. 2004. PMID: 14684332
Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide.
Casini A, Scozzafava A, Mincione F, Menabuoni L, Starnotti M, Supuran CT. Casini A, et al. Among authors: mincione f. Bioorg Med Chem Lett. 2003 Sep 1;13(17):2867-73. doi: 10.1016/s0960-894x(03)00580-8. Bioorg Med Chem Lett. 2003. PMID: 14611846
Carbonic anhydrase inhibitors: synthesis of water soluble sulfonamides incorporating a 4-sulfamoylphenylmethylthiourea scaffold, with potent intraocular pressure lowering properties.
Casini A, Scozzafava A, Mincione F, Menabuoni L, Supuran CT. Casini A, et al. Among authors: mincione f. J Enzyme Inhib Med Chem. 2002 Oct;17(5):333-43. doi: 10.1080/1475636021000010950. J Enzyme Inhib Med Chem. 2002. PMID: 12683750
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