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Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Smith MJ, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M. Smith MJ, et al. Among authors: minden md. Nat Commun. 2017 Oct 23;8(1):1099. doi: 10.1038/s41467-017-01326-5. Nat Commun. 2017. PMID: 29062045 Free PMC article.
Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling.
Louria-Hayon I, Frelin C, Ruston J, Gish G, Jin J, Kofler MM, Lambert JP, Adissu HA, Milyavsky M, Herrington R, Minden MD, Dick JE, Gingras AC, Iscove NN, Pawson T. Louria-Hayon I, et al. Among authors: minden md. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20599-604. doi: 10.1073/pnas.1319665110. Epub 2013 Dec 2. Proc Natl Acad Sci U S A. 2013. PMID: 24297922 Free PMC article.
Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.
Cumaraswamy AA, Lewis AM, Geletu M, Todic A, Diaz DB, Cheng XR, Brown CE, Laister RC, Muench D, Kerman K, Grimes HL, Minden MD, Gunning PT. Cumaraswamy AA, et al. Among authors: minden md. ACS Med Chem Lett. 2014 Sep 19;5(11):1202-1206. doi: 10.1021/ml500165r. eCollection 2014 Nov 13. ACS Med Chem Lett. 2014. PMID: 25419444 Free PMC article.
AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress.
Sriskanthadevan S, Jeyaraju DV, Chung TE, Prabha S, Xu W, Skrtic M, Jhas B, Hurren R, Gronda M, Wang X, Jitkova Y, Sukhai MA, Lin FH, Maclean N, Laister R, Goard CA, Mullen PJ, Xie S, Penn LZ, Rogers IM, Dick JE, Minden MD, Schimmer AD. Sriskanthadevan S, et al. Among authors: minden md. Blood. 2015 Mar 26;125(13):2120-30. doi: 10.1182/blood-2014-08-594408. Epub 2015 Jan 28. Blood. 2015. PMID: 25631767 Free PMC article.
529 results