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Chlorambucil-conjugated PI-polyamides (Chb-M'), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutation.
Matsui Y, Mineharu Y, Noguchi Y, Hattori EY, Kubota H, Hirata M, Miyamoto S, Sugiyama H, Arakawa Y, Kamikubo Y. Matsui Y, et al. Among authors: mineharu y. Biochem Biophys Res Commun. 2022 Sep 10;620:150-157. doi: 10.1016/j.bbrc.2022.06.090. Epub 2022 Jun 28. Biochem Biophys Res Commun. 2022. PMID: 35792512
121 results