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The UDP-glucuronosyltransferases: their role in drug metabolism and detoxification.
Rowland A, Miners JO, Mackenzie PI. Rowland A, et al. Among authors: miners jo. Int J Biochem Cell Biol. 2013 Jun;45(6):1121-32. doi: 10.1016/j.biocel.2013.02.019. Epub 2013 Mar 7. Int J Biochem Cell Biol. 2013. PMID: 23500526 Review.
Perturbation of paracetamol urinary metabolic ratios by urine flow rate.
Miners JO, Osborne NJ, Tonkin AL, Birkett DJ. Miners JO, et al. Br J Clin Pharmacol. 1992 Oct;34(4):359-62. doi: 10.1111/j.1365-2125.1992.tb05643.x. Br J Clin Pharmacol. 1992. PMID: 1457270 Free PMC article.
Interethnic differences in drug glucuronidation: a comparison of paracetamol metabolism in Caucasians and Chinese.
Osborne NJ, Tonkin AL, Miners JO. Osborne NJ, et al. Among authors: miners jo. Br J Clin Pharmacol. 1991 Dec;32(6):765-7. Br J Clin Pharmacol. 1991. PMID: 1768572 Free PMC article.
Drug glucuronidation in humans.
Miners JO, Mackenzie PI. Miners JO, et al. Pharmacol Ther. 1991;51(3):347-69. doi: 10.1016/0163-7258(91)90065-t. Pharmacol Ther. 1991. PMID: 1792239 Review.
Assessment of the drug inhibitor specificity of the human liver 4-methylumbelliferone UDP-glucuronosyltransferase activity.
Miners JO, Lillywhite KJ. Miners JO, et al. Biochem Pharmacol. 1991 Mar 1;41(5):838-41. doi: 10.1016/0006-2952(91)90090-r. Biochem Pharmacol. 1991. PMID: 1900159
Characterization of paracetamol UDP-glucuronosyltransferase activity in human liver microsomes.
Miners JO, Lillywhite KJ, Yoovathaworn K, Pongmarutai M, Birkett DJ. Miners JO, et al. Biochem Pharmacol. 1990 Aug 1;40(3):595-600. doi: 10.1016/0006-2952(90)90561-x. Biochem Pharmacol. 1990. PMID: 2116803
Along with the results of previous studies of the kinetics and inhibitor profile of human liver glucuronidation reactions (Miners et al., Biochem Pharmacol 37: 665-671, 1988 and 37: 2839-2845, 1988), these data indicate that the model glucuronidated substrates paracetamol, …
Along with the results of previous studies of the kinetics and inhibitor profile of human liver glucuronidation reactions (Miners et …
Kinetic and inhibitor studies of 4-methylumbelliferone and 1-naphthol glucuronidation in human liver microsomes.
Miners JO, Lillywhite KJ, Matthews AP, Jones ME, Birkett DJ. Miners JO, et al. Biochem Pharmacol. 1988 Feb 15;37(4):665-71. doi: 10.1016/0006-2952(88)90140-2. Biochem Pharmacol. 1988. PMID: 3124857
In vitro evidence for the involvement of at least two forms of human liver UDP-glucuronosyltransferase in morphine 3-glucuronidation.
Miners JO, Lillywhite KJ, Birkett DJ. Miners JO, et al. Biochem Pharmacol. 1988 Jul 15;37(14):2839-45. doi: 10.1016/0006-2952(88)90048-2. Biochem Pharmacol. 1988. PMID: 3134892
Overall the results provide further evidence for the heterogeneity of human liver UDPGT and, in conjunction with other recent studies (Miners JO et al., Kinetic and inhibitor studies of 4-methylumbelliferone and 1-naphthol glucuronidation in human liver microsomes, …
Overall the results provide further evidence for the heterogeneity of human liver UDPGT and, in conjunction with other recent studies (Mi
Comparison of paracetamol metabolism in young adult and elderly males.
Miners JO, Penhall R, Robson RA, Birkett DJ. Miners JO, et al. Eur J Clin Pharmacol. 1988;35(2):157-60. doi: 10.1007/BF00609245. Eur J Clin Pharmacol. 1988. PMID: 3191934
Identification of human liver cytochrome P450 isoforms mediating secondary omeprazole metabolism.
Andersson T, Miners JO, Veronese ME, Birkett DJ. Andersson T, et al. Among authors: miners jo. Br J Clin Pharmacol. 1994 Jun;37(6):597-604. doi: 10.1111/j.1365-2125.1994.tb04310.x. Br J Clin Pharmacol. 1994. PMID: 7917780 Free PMC article.
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