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Structure of minosaminomycin.
Iinuma K, Kondo S, Maeda K, Umezawa H. Iinuma K, et al. J Antibiot (Tokyo). 1975 Aug;28(8):613-5. doi: 10.7164/antibiotics.28.613. J Antibiot (Tokyo). 1975. PMID: 1158785 Free article. No abstract available.
Sulfamate-Tethered Aza-Wacker Strategy for a Kasugamine Synthon.
Mandal GH, Sathyamoorthi S. Mandal GH, et al. J Org Chem. 2024 Jan 5;89(1):793-797. doi: 10.1021/acs.joc.3c02292. Epub 2023 Dec 8. J Org Chem. 2024. PMID: 38062940 Free PMC article.
We expect that this kasugamine derivative can be used for the total syntheses of kasugamycin, minosaminomycin, and analogue antibiotics. A key step in the synthesis is our laboratory's sulfamate-tethered aza-Wacker cyclization....
We expect that this kasugamine derivative can be used for the total syntheses of kasugamycin, minosaminomycin, and analogue antibioti …
Biochemical study of minosaminomycin in relation to the kasugamycin group antibiotics.
Suzukake K, Hori M. Suzukake K, et al. J Antibiot (Tokyo). 1977 Feb;30(2):132-40. doi: 10.7164/antibiotics.30.132. J Antibiot (Tokyo). 1977. PMID: 321408 Free article.
Minosaminomycin is structurally related to kasugamycin and inhibits protein synthesis in mycobacteria. ...It is 100-times more potent than kasugamycin in this system. At 10(-7) M minosaminomycin inhibits EF-T dependent binding of aminoacyl-tRNA to ribosomes by 50%. …
Minosaminomycin is structurally related to kasugamycin and inhibits protein synthesis in mycobacteria. ...It is 100-times more potent …