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Characterisation and physical mapping of an HSV-1 glycoprotein of approximately 115 X 10(3) molecular weight.
Buckmaster EA, Gompels U, Minson A. Buckmaster EA, et al. Among authors: minson a. Virology. 1984 Dec;139(2):408-13. doi: 10.1016/0042-6822(84)90387-8. Virology. 1984. PMID: 6097034
A type-specific monoclonal antibody that efficiently neutralises HSV-1 immunoprecipitated a glycoprotein of slightly greater electrophoretic mobility than gB from HSV-1 infected cells. ...Antibody LP11 inhibits plaque formation when added to cell monolayers after in
A type-specific monoclonal antibody that efficiently neutralises HSV-1 immunoprecipitated a glycoprotein of slightly greater e
Virus-specific DNA sequences present in cells which carry the herpes simplex virus thymidine kinase gene.
Minson AC, Darby GK, Wildy P. Minson AC, et al. J Gen Virol. 1979 Nov;45(2):489-96. doi: 10.1099/0022-1317-45-2-489. J Gen Virol. 1979. PMID: 232133
Both cell lines contained 1 to 3 copies per cell of a sequence lying within map co-ordinates 0.2 to 0.4 of the HSV-2 genome. ...The failure of EcoR1-restricted HSV-2 DNA to act as a donor of the thymidine kinase gene in transformation experiments suggests that the g …
Both cell lines contained 1 to 3 copies per cell of a sequence lying within map co-ordinates 0.2 to 0.4 of the HSV-2 genome. ...The f …
Characterization of herpes simplex virus type 1 recombinants with mutations in the cytoplasmic tail of glycoprotein H.
Browne HM, Bruun BC, Minson AC. Browne HM, et al. Among authors: minson ac. J Gen Virol. 1996 Oct;77 ( Pt 10):2569-73. doi: 10.1099/0022-1317-77-10-2569. J Gen Virol. 1996. PMID: 8887492
Previous studies have pointed to a requirement for certain amino acid residues of the cytoplasmic tail of gH in these processes. ...Viruses containing a deletion of the SVP motif, or in which the valine residue of this triplet was replaced by alanine, entered cells …
Previous studies have pointed to a requirement for certain amino acid residues of the cytoplasmic tail of gH in these processes. ...V …
Mutations in the cytoplasmic tail of herpes simplex virus glycoprotein H suppress cell fusion by a syncytial strain.
Wilson DW, Davis-Poynter N, Minson AC. Wilson DW, et al. Among authors: minson ac. J Virol. 1994 Nov;68(11):6985-93. doi: 10.1128/JVI.68.11.6985-6993.1994. J Virol. 1994. PMID: 7933080 Free PMC article.
We have developed a complementation assay, using transiently transfected COS cells, to facilitate a molecular analysis of the herpes simplex virus type 1 glycoprotein gH. When infected by a gH-null syncytial virus, COS cells expressing wild-type gH generate i …
We have developed a complementation assay, using transiently transfected COS cells, to facilitate a molecular analysis of the …
Antigenic analysis of a major neutralization site of herpes simplex virus glycoprotein D, using deletion mutants and monoclonal antibody-resistant mutants.
Muggeridge MI, Isola VJ, Byrn RA, Tucker TJ, Minson AC, Glorioso JC, Cohen GH, Eisenberg RJ. Muggeridge MI, et al. Among authors: minson ac. J Virol. 1988 Sep;62(9):3274-80. doi: 10.1128/JVI.62.9.3274-3280.1988. J Virol. 1988. PMID: 2841479 Free PMC article.
Herpes simplex virus glycoprotein D is a component of the virion envelope and appears to be involved in attachment, penetration, and cell fusion. Monoclonal antibodies against this protein can be arranged in groups on the basis of a number of biological and biochemi …
Herpes simplex virus glycoprotein D is a component of the virion envelope and appears to be involved in attachment, penetration, and …
An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization.
Minson AC, Hodgman TC, Digard P, Hancock DC, Bell SE, Buckmaster EA. Minson AC, et al. J Gen Virol. 1986 Jun;67 ( Pt 6):1001-13. doi: 10.1099/0022-1317-67-6-1001. J Gen Virol. 1986. PMID: 2423636
Each antibody selected a substitution from different parts of the molecule and mutants resistant to a single antibody always arose from the same mutation. ...One antibody had neither activity but enhanced the infectivity of HSV-2 in a type-specific manner. Th …
Each antibody selected a substitution from different parts of the molecule and mutants resistant to a single antibody always a …
The role of herpes simplex virus type 1 thymidine kinase in pathogenesis.
Efstathiou S, Kemp S, Darby G, Minson AC. Efstathiou S, et al. Among authors: minson ac. J Gen Virol. 1989 Apr;70 ( Pt 4):869-79. doi: 10.1099/0022-1317-70-4-869. J Gen Virol. 1989. PMID: 2543763
A genetically engineered herpes simplex virus type 1 (HSV-1)thymidine kinase (TK) deletion mutant has been constructed and used to investigate the role of this gene in pathogenesis. ...
A genetically engineered herpes simplex virus type 1 (HSV-1)thymidine kinase (TK) deletion mutant has been constructed and used to in
The use of monoclonal antibodies in (reverse) passive haemagglutination tests for herpes simplex virus antigens and antibodies.
Cranage MP, McLean CS, Buckmaster EA, Minson AC, Wildy P, Coombs RR. Cranage MP, et al. Among authors: minson ac. J Med Virol. 1983;11(4):295-306. doi: 10.1002/jmv.1890110405. J Med Virol. 1983. PMID: 6308140
A further monoclonal antibody with specificity for the major DNA-binding protein of type 2 herpes virus-infected cells (a nonstructural protein) showed conventional reverse passive haemagglutination when linked to red blood cells and was specific for type 2 herpes s
A further monoclonal antibody with specificity for the major DNA-binding protein of type 2 herpes virus-infected cells (a nons
Detection of herpes simplex virus-specific DNA sequences in latently infected mice and in humans.
Efstathiou S, Minson AC, Field HJ, Anderson JR, Wildy P. Efstathiou S, et al. Among authors: minson ac. J Virol. 1986 Feb;57(2):446-55. doi: 10.1128/JVI.57.2.446-455.1986. J Virol. 1986. PMID: 3003377 Free PMC article.
This "endless" herpes simplex virus DNA is both qualitatively and quantitatively stable in mouse neural tissue analyzed over a 4-month period. ...
This "endless" herpes simplex virus DNA is both qualitatively and quantitatively stable in mouse neural tissue analyzed over a 4-mont …
Characterization of the 92,000-dalton glycoprotein induced by herpes simplex virus type 2.
Marsden HS, Buckmaster A, Palfreyman JW, Hope RG, Minson AC. Marsden HS, et al. Among authors: minson ac. J Virol. 1984 May;50(2):547-54. doi: 10.1128/JVI.50.2.547-554.1984. J Virol. 1984. PMID: 6323754 Free PMC article.
Third, by using HSV type 1/HSV type 2 intertypic recombinants and a simple radioimmunoassay, the target antigen of the two monoclonal antibodies was shown to map in the same region as g92K (0.846 to 0.924). Fourth, the intertypic recombinant R12-3 was shown by sodium dodec …
Third, by using HSV type 1/HSV type 2 intertypic recombinants and a simple radioimmunoassay, the target antigen of the two monoclonal …
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