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Lipotoxicity disrupts incretin-regulated human β cell connectivity.
Hodson DJ, Mitchell RK, Bellomo EA, Sun G, Vinet L, Meda P, Li D, Li WH, Bugliani M, Marchetti P, Bosco D, Piemonti L, Johnson P, Hughes SJ, Rutter GA. Hodson DJ, et al. Among authors: mitchell rk. J Clin Invest. 2013 Oct;123(10):4182-94. doi: 10.1172/JCI68459. Epub 2013 Sep 9. J Clin Invest. 2013. PMID: 24018562 Free PMC article.
Incretin-modulated beta cell energetics in intact islets of Langerhans.
Hodson DJ, Tarasov AI, Gimeno Brias S, Mitchell RK, Johnston NR, Haghollahi S, Cane MC, Bugliani M, Marchetti P, Bosco D, Johnson PR, Hughes SJ, Rutter GA. Hodson DJ, et al. Among authors: mitchell rk. Mol Endocrinol. 2014 Jun;28(6):860-71. doi: 10.1210/me.2014-1038. Epub 2014 Apr 25. Mol Endocrinol. 2014. PMID: 24766140 Free PMC article.
ADCY5 couples glucose to insulin secretion in human islets.
Hodson DJ, Mitchell RK, Marselli L, Pullen TJ, Gimeno Brias S, Semplici F, Everett KL, Cooper DM, Bugliani M, Marchetti P, Lavallard V, Bosco D, Piemonti L, Johnson PR, Hughes SJ, Li D, Li WH, Shapiro AM, Rutter GA. Hodson DJ, et al. Among authors: mitchell rk. Diabetes. 2014 Sep;63(9):3009-21. doi: 10.2337/db13-1607. Epub 2014 Apr 16. Diabetes. 2014. PMID: 24740569 Free PMC article.
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose.
Johnston NR, Mitchell RK, Haythorne E, Pessoa MP, Semplici F, Ferrer J, Piemonti L, Marchetti P, Bugliani M, Bosco D, Berishvili E, Duncanson P, Watkinson M, Broichhagen J, Trauner D, Rutter GA, Hodson DJ. Johnston NR, et al. Among authors: mitchell rk. Cell Metab. 2016 Sep 13;24(3):389-401. doi: 10.1016/j.cmet.2016.06.020. Epub 2016 Jul 21. Cell Metab. 2016. PMID: 27452146 Free PMC article.
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