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Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy.
Flores C, Wildes T, Dean BD, Moore G, Drake J, Abraham R, Gil J, Yegorov O, Yang C, Dean J, Moneypenny C, Shin D, Pham C, Krauser J, King J, Grant G, Driscoll T, Kurtzberg J, McLendon R, Gururangan S, Mitchell D. Flores C, et al. Among authors: mitchell d. Sci Adv. 2019 Nov 27;5(11):eaav9879. doi: 10.1126/sciadv.aav9879. eCollection 2019 Nov. Sci Adv. 2019. PMID: 31807694 Free PMC article.
Adoptive immunotherapy for malignant glioma.
Mitchell DA, Fecci PE, Sampson JH. Mitchell DA, et al. Cancer J. 2003 May-Jun;9(3):157-66. doi: 10.1097/00130404-200305000-00004. Cancer J. 2003. PMID: 12952301 Review.
EGFRvIII-targeted vaccination therapy of malignant glioma.
Choi BD, Archer GE, Mitchell DA, Heimberger AB, McLendon RE, Bigner DD, Sampson JH. Choi BD, et al. Among authors: mitchell da. Brain Pathol. 2009 Oct;19(4):713-23. doi: 10.1111/j.1750-3639.2009.00318.x. Brain Pathol. 2009. PMID: 19744042 Free PMC article. Review.
Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma.
Sampson JH, Aldape KD, Archer GE, Coan A, Desjardins A, Friedman AH, Friedman HS, Gilbert MR, Herndon JE, McLendon RE, Mitchell DA, Reardon DA, Sawaya R, Schmittling R, Shi W, Vredenburgh JJ, Bigner DD, Heimberger AB. Sampson JH, et al. Among authors: mitchell da. Neuro Oncol. 2011 Mar;13(3):324-33. doi: 10.1093/neuonc/noq157. Epub 2010 Dec 10. Neuro Oncol. 2011. PMID: 21149254 Free PMC article. Clinical Trial.
Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.
Mitchell DA, Cui X, Schmittling RJ, Sanchez-Perez L, Snyder DJ, Congdon KL, Archer GE, Desjardins A, Friedman AH, Friedman HS, Herndon JE 2nd, McLendon RE, Reardon DA, Vredenburgh JJ, Bigner DD, Sampson JH. Mitchell DA, et al. Blood. 2011 Sep 15;118(11):3003-12. doi: 10.1182/blood-2011-02-334565. Epub 2011 Jul 18. Blood. 2011. PMID: 21768296 Free PMC article. Clinical Trial.
Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.
Sanchez-Perez LA, Choi BD, Archer GE, Cui X, Flores C, Johnson LA, Schmittling RJ, Snyder D, Herndon JE 2nd, Bigner DD, Mitchell DA, Sampson JH. Sanchez-Perez LA, et al. Among authors: mitchell da. PLoS One. 2013;8(3):e59082. doi: 10.1371/journal.pone.0059082. Epub 2013 Mar 18. PLoS One. 2013. PMID: 23527092 Free PMC article.
4,319 results