Mitchell DJ - Search Results

1

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease.

Youssef S, Stüve O, Patarroyo JC, Ruiz PJ, Radosevich JL, Hur EM, Bravo M, Mitchell DJ, Sobel RA, Steinman L, Zamvil SS. Youssef S, et al. Among authors: mitchell dj. Nature. 2002 Nov 7;420(6911):78-84. doi: 10.1038/nature01158. Nature. 2002. PMID: 12422218

2

Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis.

Robinson WH, Fontoura P, Lee BJ, de Vegvar HE, Tom J, Pedotti R, DiGennaro CD, Mitchell DJ, Fong D, Ho PP, Ruiz PJ, Maverakis E, Stevens DB, Bernard CC, Martin R, Kuchroo VK, van Noort JM, Genain CP, Amor S, Olsson T, Utz PJ, Garren H, Steinman L. Robinson WH, et al. Among authors: mitchell dj. Nat Biotechnol. 2003 Sep;21(9):1033-9. doi: 10.1038/nbt859. Epub 2003 Aug 10. Nat Biotechnol. 2003. PMID: 12910246

3

Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis.

Shachaf CM, Perez OD, Youssef S, Fan AC, Elchuri S, Goldstein MJ, Shirer AE, Sharpe O, Chen J, Mitchell DJ, Chang M, Nolan GP, Steinman L, Felsher DW. Shachaf CM, et al. Among authors: mitchell dj. Blood. 2007 Oct 1;110(7):2674-84. doi: 10.1182/blood-2006-09-048033. Epub 2007 Jul 10. Blood. 2007. PMID: 17622571 Free PMC article.

4

Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine.

Karpuj MV, Becher MW, Springer JE, Chabas D, Youssef S, Pedotti R, Mitchell D, Steinman L. Karpuj MV, et al. Nat Med. 2002 Feb;8(2):143-9. doi: 10.1038/nm0202-143. Nat Med. 2002. PMID: 11821898

5

Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination.

Pedotti R, DeVoss JJ, Youssef S, Mitchell D, Wedemeyer J, Madanat R, Garren H, Fontoura P, Tsai M, Galli SJ, Sobel RA, Steinman L. Pedotti R, et al. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1867-72. doi: 10.1073/pnas.252777399. Epub 2003 Feb 7. Proc Natl Acad Sci U S A. 2003. PMID: 12576552 Free PMC article.

6

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination.

Zamvil S, Nelson P, Trotter J, Mitchell D, Knobler R, Fritz R, Steinman L. Zamvil S, et al. Nature. 1985 Sep 26-Oct 2;317(6035):355-8. doi: 10.1038/317355a0. Nature. 1985. PMID: 2413363

7

Selection for T-cell receptor V beta-D beta-J beta gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis.

Oksenberg JR, Panzara MA, Begovich AB, Mitchell D, Erlich HA, Murray RS, Shimonkevitz R, Sherritt M, Rothbard J, Bernard CC, Steinman L. Oksenberg JR, et al. Nature. 1993 Mar 4;362(6415):68-70. doi: 10.1038/362068a0. Nature. 1993. PMID: 7680433

8

Selective and nonselective stages in homing of T lymphocytes to the central nervous system during experimental allergic encephalomyelitis.

Karin N, Szafer F, Mitchell D, Gold DP, Steinman L. Karin N, et al. J Immunol. 1993 May 1;150(9):4116-24. J Immunol. 1993. PMID: 8386207

9

Treatment of experimental encephalomyelitis with a peptide analogue of myelin basic protein.

Brocke S, Gijbels K, Allegretta M, Ferber I, Piercy C, Blankenstein T, Martin R, Utz U, Karin N, Mitchell D, Veromaa T, Waisman A, Gaur A, Conlon P, Ling N, Fairchild PJ, Wraith DC, O'Garra A, Fathman CG, Steinman L. Brocke S, et al. Nature. 1996 Jan 25;379(6563):343-6. doi: 10.1038/379343a0. Nature. 1996. PMID: 8552189

10

The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease.

Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. Chabas D, et al. Science. 2001 Nov 23;294(5547):1731-5. doi: 10.1126/science.1062960. Science. 2001. PMID: 11721059

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