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Preclinical Development of ONC1-13B, Novel Antiandrogen for Prostate Cancer Treatment.
Ivachtchenko AV, Mitkin OD, Kudan EV, Rjahovsky AA, Vorobiev AA, Trifelenkov AS, Shevkun NA, Proskurina OV, Kravchenko DV, Karapetian RN. Ivachtchenko AV, et al. Among authors: mitkin od. J Cancer. 2014 Jan 21;5(2):133-42. doi: 10.7150/jca.7773. eCollection 2014. J Cancer. 2014. PMID: 24494031 Free PMC article.
Design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists.
Ivachtchenko AV, Ivanenkov YA, Mitkin OD, Vorobiev AA, Kuznetsova IV, Shevkun NA, Koryakova AG, Karapetian RN, Trifelenkov AS, Kravchenko DV, Veselov MS, Chufarova NV. Ivachtchenko AV, et al. Among authors: mitkin od. Eur J Med Chem. 2015 Jun 24;99:51-66. doi: 10.1016/j.ejmech.2015.05.039. Epub 2015 Jun 2. Eur J Med Chem. 2015. PMID: 26046313
Antagonists of 5-HT₆ receptors. Substituted 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[3,4-e]pyrimidines and 3-(phenylsulfonyl)pyrazolo[1,5-a]pyrido[4,3-d]pyrimidines-Synthesis and 'structure-activity' relationship.
Ivachtchenko AV, Golovina ES, Kadieva MG, Kysil VM, Mitkin OD, Vorobiev AA, Okun I. Ivachtchenko AV, et al. Among authors: mitkin od. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4273-80. doi: 10.1016/j.bmcl.2012.05.036. Epub 2012 May 17. Bioorg Med Chem Lett. 2012. PMID: 22664127
Novel oral anti-influenza prodrug candidate AV5075S.
Ivachtchenko AV, Ivanenkov YA, Mitkin OD, Yamanushkin PM, Bichko VV, Shevkun NA, Mokrushina OV, Nevolina OO, Karapetian RN, Leneva IA, Fedyakina IT, Veselov MS. Ivachtchenko AV, et al. Among authors: mitkin od. J Antimicrob Chemother. 2014 May;69(5):1311-24. doi: 10.1093/jac/dkt507. Epub 2014 Jan 15. J Antimicrob Chemother. 2014. PMID: 24428978
Novel oral anti-influenza drug candidate AV5080.
Ivachtchenko AV, Ivanenkov YA, Mitkin OD, Yamanushkin PM, Bichko VV, Shevkun NA, Karapetian RN, Leneva IA, Borisova OV, Veselov MS. Ivachtchenko AV, et al. Among authors: mitkin od. J Antimicrob Chemother. 2014 Jul;69(7):1892-902. doi: 10.1093/jac/dku074. Epub 2014 Apr 11. J Antimicrob Chemother. 2014. PMID: 24729605
Discovery of novel highly potent hepatitis C virus NS5A inhibitor (AV4025).
Ivachtchenko AV, Mitkin OD, Yamanushkin PM, Kuznetsova IV, Bulanova EA, Shevkun NA, Koryakova AG, Karapetian RN, Bichko VV, Trifelenkov AS, Kravchenko DV, Vostokova NV, Veselov MS, Chufarova NV, Ivanenkov YA. Ivachtchenko AV, et al. Among authors: mitkin od. J Med Chem. 2014 Sep 25;57(18):7716-30. doi: 10.1021/jm500951r. Epub 2014 Sep 9. J Med Chem. 2014. PMID: 25148100
Non-rigid Diarylmethyl Analogs of Baloxavir as Cap-Dependent Endonuclease Inhibitors of Influenza Viruses.
Ivashchenko AA, Mitkin OD, Jones JC, Nikitin AV, Koryakova AG, Ryakhovskiy A, Karapetian RN, Kravchenko DV, Aladinskiy V, Leneva IA, Falynskova IN, Glubokova EA, Govorkova EA, Ivachtchenko AV. Ivashchenko AA, et al. Among authors: mitkin od. J Med Chem. 2020 Sep 10;63(17):9403-9420. doi: 10.1021/acs.jmedchem.0c00565. Epub 2020 Aug 17. J Med Chem. 2020. PMID: 32787099
Synthesis, inhibitory activity and oral dosing formulation of AV5124, the structural analogue of influenza virus endonuclease inhibitor baloxavir.
Ivashchenko AA, Mitkin OD, Jones JC, Nikitin AV, Koryakova AG, Karapetian RN, Kravchenko DV, Mochalov SV, Ryakhovskiy AA, Aladinskiy V, Leneva IA, Falynskova IN, Glubokova EA, Govorkova EA, Ivachtchenko AV. Ivashchenko AA, et al. Among authors: mitkin od. J Antimicrob Chemother. 2021 Mar 12;76(4):1010-1018. doi: 10.1093/jac/dkaa524. J Antimicrob Chemother. 2021. PMID: 33367751 Free PMC article.
40 results