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Mitochondrial DNA content in embryo culture medium is significantly associated with human embryo fragmentation.
Stigliani S, Anserini P, Venturini PL, Scaruffi P. Stigliani S, et al. Hum Reprod. 2013 Oct;28(10):2652-60. doi: 10.1093/humrep/det314. Epub 2013 Jul 25. Hum Reprod. 2013. PMID: 23887072 Clinical Trial.
SUMMARY ANSWER: The mitochondrial DNA (mtDNA) content of culture medium is significantly associated with the fragmentation rate on Days 2 and 3 of embryo development, whether the oocyte came from women ≤ 35 or >35 years old. ...After DNA puri …
SUMMARY ANSWER: The mitochondrial DNA (mtDNA) content of culture medium is significantly associated with the fragmentat …
Non-invasive mitochondrial DNA quantification on Day 3 predicts blastocyst development: a prospective, blinded, multi-centric study.
Stigliani S, Orlando G, Massarotti C, Casciano I, Bovis F, Anserini P, Ubaldi FM, Remorgida V, Rienzi L, Scaruffi P. Stigliani S, et al. Mol Hum Reprod. 2019 Sep 1;25(9):527-537. doi: 10.1093/molehr/gaz032. Mol Hum Reprod. 2019. PMID: 31174207
In ART, embryo quality evaluation is routinely based on morphological criteria. We previously demonstrated that the mitochondrial DNA (mtDNA)/genomic DNA (gDNA) ratio in culture medium was significantly associated with embryo quality and viabili …
In ART, embryo quality evaluation is routinely based on morphological criteria. We previously demonstrated that the mitochondrial
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