Mitochondrial Haplogroups Affect Severity But Not Prevalence of Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2017.
PMID: 28245487
Free PMC article.
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mitochondrial haplogroups affect severity but not prevalence of diabetes ic retinopathy.
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Mitochondrial Haplogroups Affect Severity But Not Prevalence of Diabetic Retinopathy. instead
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Biomarkers of mitochondrial dysfunction in autism spectrum disorder: A systematic review and meta-analysis.
Neurobiol Dis. 2024 Jul;197:106520. doi: 10.1016/j.nbd.2024.106520. Epub 2024 May 3.
Neurobiol Dis. 2024.
PMID: 38703861
Free article.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting 1 in 36 children and is associated with physiological abnormalities, most notably mitochondrial dysfunction, at least in a subset of individuals. ...Meta-analyses discovered significant differ …
Autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting 1 in 36 children and is associated with physiological abnor …
Mitochondrial Haplogroups Affect Severity But Not Prevalence of Diabetic Retinopathy.
Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1346-1351. doi: 10.1167/iovs.16-20616.
Invest Ophthalmol Vis Sci. 2017.
PMID: 28245487
Free PMC article.
PURPOSE: We previously reported European mitochondrial haplogroup H to be a risk factor for and haplogroup UK to be protective against proliferative diabetic retinopathy (PDR) among Caucasian patients with diabetic retinopathy (DR) …
PURPOSE: We previously reported European mitochondrial haplogroup H to be a risk factor for and haplogroup UK to be pro …
Mitochondrial haplogroups are associated with severity of diabetic retinopathy.
Invest Ophthalmol Vis Sci. 2014 Aug 12;55(9):5589-95. doi: 10.1167/iovs.14-15149.
Invest Ophthalmol Vis Sci. 2014.
PMID: 25118268
Free PMC article.
PURPOSE: To determine if specific mitochondrial haplogroups associate with nonproliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR). ...We tested for an association between mitochondrial haplogro …
PURPOSE: To determine if specific mitochondrial haplogroups associate with nonproliferative diabetic retinopathy …
"Mitochondrial pathogenic mutations and metabolic alterations associated with COVID-19 disease severity".
J Med Virol. 2023 Feb;95(2):e28553. doi: 10.1002/jmv.28553.
J Med Virol. 2023.
PMID: 36832542
Mitochondrial mutations have been found to be associated with several respiratory diseases. ...The present study aims to elucidate the role of mitochondrial DNA (mtDNA) mutations, mitochondrial haplogroup, and energy metabolism in disease sev …
Mitochondrial mutations have been found to be associated with several respiratory diseases. ...The present study aims to eluci …
Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation.
Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2212417119. doi: 10.1073/pnas.2212417119. Epub 2022 Nov 2.
Proc Natl Acad Sci U S A. 2022.
PMID: 36322731
Free PMC article.
Analysis of the maternally inherited mtDNA revealed a novel genotype encompassing the haplogroup J - defining mitochondrial DNA (mtDNA) ND5 m.13708G>A (A458T) variant arising on the mtDNA haplogroup H7A background, an extremely rare combination. ...Thus, c …
Analysis of the maternally inherited mtDNA revealed a novel genotype encompassing the haplogroup J - defining mitochondrial DN …
Dissecting the multifaceted contribution of the mitochondrial genome to autism spectrum disorder.
Front Genet. 2022 Nov 7;13:953762. doi: 10.3389/fgene.2022.953762. eCollection 2022.
Front Genet. 2022.
PMID: 36419830
Free PMC article.
Multivariable regression analyses indicated that variants with 15%-5% heteroplasmy in probands are associated to a greater severity of ASD based on ADOS-2 criteria, whereas paternal super-haplogroups H and JT were associated with milder phenotypes. ...The unexpected …
Multivariable regression analyses indicated that variants with 15%-5% heteroplasmy in probands are associated to a greater severity o …
Mitochondrial DNA haplogroup analysis in Saudi Arab patients with multiple sclerosis.
PLoS One. 2022 Dec 19;17(12):e0279237. doi: 10.1371/journal.pone.0279237. eCollection 2022.
PLoS One. 2022.
PMID: 36534684
Free PMC article.
All patients and controls could be classified into ten haplogroups. The European-specific haplogroup U was more prevalent in patients than in the controls (26.1% vs. 4.2%), whereas haplogroup T was only present in patients and haplogroups HV and …
All patients and controls could be classified into ten haplogroups. The European-specific haplogroup U was more prevalent …
Mitochondrial DNA haplogroups modulate the radiographic progression of Spanish patients with osteoarthritis.
Rheumatol Int. 2015 Feb;35(2):337-44. doi: 10.1007/s00296-014-3104-1. Epub 2014 Aug 3.
Rheumatol Int. 2015.
PMID: 25086630
Taking into account the incidence of the mitochondria and the mtDNA haplogroups in the pathogenesis of OA, the main objective of this work was to evaluate the incidence of the mtDNA haplogroups in the radiographic progression of the OA disease in a well-chara …
Taking into account the incidence of the mitochondria and the mtDNA haplogroups in the pathogenesis of OA, the main objective …
Differential effects of cisplatin on cybrid cells with varying mitochondrial DNA haplogroups.
PeerJ. 2020 Oct 1;8:e9908. doi: 10.7717/peerj.9908. eCollection 2020.
PeerJ. 2020.
PMID: 33062421
Free PMC article.
There is accumulating evidence that an individual's mitochondrial (mt) DNA may play a role in their response to medications. Variations within mtDNA can be observed, and an individual's mtDNA can be categorized into haplogroups that are defined by accumulations of s …
There is accumulating evidence that an individual's mitochondrial (mt) DNA may play a role in their response to medications. Variatio …
The role of mitochondrial DNA variants and dysfunction in the pathogenesis and progression of multiple sclerosis.
Mitochondrion. 2025 Mar;81:102002. doi: 10.1016/j.mito.2024.102002. Epub 2024 Dec 26.
Mitochondrion. 2025.
PMID: 39732186
Review.
Recent studies showed mitochondrial DNA (mtDNA) as a potential player in the development and progression of MS. ...Several studies have reported an association between mtDNA variants and increased susceptibility to MS, while others have found a link between mtDNA copy numb …
Recent studies showed mitochondrial DNA (mtDNA) as a potential player in the development and progression of MS. ...Several studies ha …
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