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New methods to titrate EIAV-based lentiviral vectors.
Martin-Rendon E, White LJ, Olsen A, Mitrophanous KA, Mazarakis ND. Martin-Rendon E, et al. Among authors: mitrophanous ka. Mol Ther. 2002 May;5(5 Pt 1):566-70. doi: 10.1006/mthe.2002.0576. Mol Ther. 2002. PMID: 11991747
Minimal requirement for a lentivirus vector based on human immunodeficiency virus type 1.
Kim VN, Mitrophanous K, Kingsman SM, Kingsman AJ. Kim VN, et al. J Virol. 1998 Jan;72(1):811-6. doi: 10.1128/JVI.72.1.811-816.1998. J Virol. 1998. PMID: 9420292 Free PMC article.
Stable gene transfer to the nervous system using a non-primate lentiviral vector.
Mitrophanous K, Yoon S, Rohll J, Patil D, Wilkes F, Kim V, Kingsman S, Kingsman A, Mazarakis N. Mitrophanous K, et al. Gene Ther. 1999 Nov;6(11):1808-18. doi: 10.1038/ Gene Ther. 1999. PMID: 10602376
Growth factor enhanced retroviral gene transfer to the adult central nervous system.
King LA, Mitrophanous KA, Clark LA, Kim VN, Rohll JB, Kingsman AJ, Colello RJ. King LA, et al. Among authors: mitrophanous ka. Gene Ther. 2000 Jul;7(13):1103-11. doi: 10.1038/ Gene Ther. 2000. PMID: 10918476
Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery.
Mazarakis ND, Azzouz M, Rohll JB, Ellard FM, Wilkes FJ, Olsen AL, Carter EE, Barber RD, Baban DF, Kingsman SM, Kingsman AJ, O'Malley K, Mitrophanous KA. Mazarakis ND, et al. Among authors: mitrophanous ka. Hum Mol Genet. 2001 Sep 15;10(19):2109-21. doi: 10.1093/hmg/10.19.2109. Hum Mol Genet. 2001. PMID: 11590128
Design, production, safety, evaluation, and clinical applications of nonprimate lentiviral vectors.
Rohll JB, Mitrophanous KA, Martin-Rendon E, Ellard FM, Radcliffe PA, Mazarakis ND, Kingsman SM. Rohll JB, et al. Among authors: mitrophanous ka. Methods Enzymol. 2002;346:466-500. doi: 10.1016/s0076-6879(02)46072-7. Methods Enzymol. 2002. PMID: 11883086 No abstract available.
Gene transduction efficiency in cells of different species by HIV and EIAV vectors.
Ikeda Y, Collins MK, Radcliffe PA, Mitrophanous KA, Takeuchi Y. Ikeda Y, et al. Among authors: mitrophanous ka. Gene Ther. 2002 Jul;9(14):932-8. doi: 10.1038/ Gene Ther. 2002. PMID: 12085241
Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease.
Azzouz M, Martin-Rendon E, Barber RD, Mitrophanous KA, Carter EE, Rohll JB, Kingsman SM, Kingsman AJ, Mazarakis ND. Azzouz M, et al. Among authors: mitrophanous ka. J Neurosci. 2002 Dec 1;22(23):10302-12. doi: 10.1523/JNEUROSCI.22-23-10302.2002. J Neurosci. 2002. PMID: 12451130 Free PMC article.
Long-term replacement of a mutated nonfunctional CNS gene: reversal of hypothalamic diabetes insipidus using an EIAV-based lentiviral vector expressing arginine vasopressin.
Bienemann AS, Martin-Rendon E, Cosgrave AS, Glover CP, Wong LF, Kingsman SM, Mitrophanous KA, Mazarakis ND, Uney JB. Bienemann AS, et al. Among authors: mitrophanous ka. Mol Ther. 2003 May;7(5 Pt 1):588-96. doi: 10.1016/s1525-0016(03)00069-8. Mol Ther. 2003. PMID: 12718901
Long-term transgene expression by administration of a lentivirus-based vector to the fetal circulation of immuno-competent mice.
Waddington SN, Mitrophanous KA, Ellard FM, Buckley SM, Nivsarkar M, Lawrence L, Cook HT, Al-Allaf F, Bigger B, Kingsman SM, Coutelle C, Themis M. Waddington SN, et al. Among authors: mitrophanous ka. Gene Ther. 2003 Aug;10(15):1234-40. doi: 10.1038/ Gene Ther. 2003. PMID: 12858188
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