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Targeted and highly efficient gene transfer into CD4+ cells by a recombinant human immunodeficiency virus retroviral vector.
Shimada T, Fujii H, Mitsuya H, Nienhuis AW. Shimada T, et al. Among authors: mitsuya h. J Clin Invest. 1991 Sep;88(3):1043-7. doi: 10.1172/JCI115365. J Clin Invest. 1991. PMID: 1885765 Free PMC article.
Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines.
Siddiqui MA, Driscoll JS, Marquez VE, Roth JS, Shirasaka T, Mitsuya H, Barchi JJ Jr, Kelley JA. Siddiqui MA, et al. Among authors: mitsuya h. J Med Chem. 1992 Jun 12;35(12):2195-201. doi: 10.1021/jm00090a008. J Med Chem. 1992. PMID: 1351945
The 2'-F-dd-uridine analogues 7a-d (with H, F, Cl, and CH3 substitution in the 5-position) as well as the 4-deoxy compound (12b) are nonprotective to ATH8 or CEM cells infected with HIV-1. ...A small amount of 2'-F-dd-ara-U (7a) is formed from 10a in monkey plasma after gr …
The 2'-F-dd-uridine analogues 7a-d (with H, F, Cl, and CH3 substitution in the 5-position) as well as the 4-deoxy compound (12b) are …
The immunology of HIV infection: implications for therapy.
Yarchoan R, Mitsuya H, Broder S. Yarchoan R, et al. Among authors: mitsuya h. AIDS Res Hum Retroviruses. 1992 Jun;8(6):1023-31. doi: 10.1089/aid.1992.8.1023. AIDS Res Hum Retroviruses. 1992. PMID: 1503817 Review.
In vitro inhibition of human immunodeficiency virus (HIV) type 1 replication by C2 symmetry-based HIV protease inhibitors as single agents or in combinations.
Kageyama S, Weinstein JN, Shirasaka T, Kempf DJ, Norbeck DW, Plattner JJ, Erickson J, Mitsuya H. Kageyama S, et al. Among authors: mitsuya h. Antimicrob Agents Chemother. 1992 May;36(5):926-33. doi: 10.1128/aac.36.5.926. Antimicrob Agents Chemother. 1992. PMID: 1510415 Free PMC article.
Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleosides 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine.
Hartman NR, Ahluwalia GS, Cooney DA, Mitsuya H, Kageyama S, Fridland A, Broder S, Johns DG. Hartman NR, et al. Among authors: mitsuya h. Mol Pharmacol. 1991 Jul;40(1):118-24. Mol Pharmacol. 1991. PMID: 1677450
In vitro inhibition of the infectivity and replication of human immunodeficiency virus type 1 by combination of antiretroviral 2',3'-dideoxynucleosides and virus-binding inhibitors.
Hayashi S, Fine RL, Chou TC, Currens MJ, Broder S, Mitsuya H. Hayashi S, et al. Among authors: mitsuya h. Antimicrob Agents Chemother. 1990 Jan;34(1):82-8. doi: 10.1128/aac.34.1.82. Antimicrob Agents Chemother. 1990. PMID: 1691616 Free PMC article.
Differences in the interaction of HIV-1 and HIV-2 with CD4.
Looney DJ, Hayashi S, Nicklas M, Redfield RR, Broder S, Wong-Staal F, Mitsuya H. Looney DJ, et al. Among authors: mitsuya h. J Acquir Immune Defic Syndr (1988). 1990;3(7):649-57. J Acquir Immune Defic Syndr (1988). 1990. PMID: 1693676
NIH conference. Antiretroviral therapy in AIDS.
Broder S, Mitsuya H, Yarchoan R, Pavlakis GN. Broder S, et al. Among authors: mitsuya h. Ann Intern Med. 1990 Oct 15;113(8):604-18. doi: 10.7326/0003-4819-113-8-604. Ann Intern Med. 1990. PMID: 1698042 Review.
Immunologic issues in anti-retroviral therapy.
Yarchoan R, Mitsuya H, Broder S. Yarchoan R, et al. Among authors: mitsuya h. Immunol Today. 1990 Sep;11(9):327-33. doi: 10.1016/0167-5699(90)90128-v. Immunol Today. 1990. PMID: 1698379 Review.
However, as Robert Yarchoan, Hiroaki Mitsuya and Samuel Broder point out, complete immunoreconstitution generally does not occur in patients with established AIDS using currently available therapies. ...
However, as Robert Yarchoan, Hiroaki Mitsuya and Samuel Broder point out, complete immunoreconstitution generally does not occur in p …
Molecular targets for AIDS therapy.
Mitsuya H, Yarchoan R, Broder S. Mitsuya H, et al. Science. 1990 Sep 28;249(4976):1533-44. doi: 10.1126/science.1699273. Science. 1990. PMID: 1699273 Review.
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