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Insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: peroxisome proliferator-activated receptor gamma agonist improves defective activation of atypical protein kinase C.
Ortmeyer HK, Sajan MP, Miura A, Kanoh Y, Rivas J, Li Y, Standaert ML, Ryan AS, Bodkin NL, Farese RV, Hansen BC. Ortmeyer HK, et al. Among authors: miura a. Antioxid Redox Signal. 2011 Jan 15;14(2):207-19. doi: 10.1089/ars.2010.3234. Epub 2010 Nov 23. Antioxid Redox Signal. 2011. PMID: 20518698 Free PMC article.
Activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 is defective in muscle in type 2 diabetes and impaired glucose tolerance: amelioration by rosiglitazone and exercise.
Beeson M, Sajan MP, Dizon M, Grebenev D, Gomez-Daspet J, Miura A, Kanoh Y, Powe J, Bandyopadhyay G, Standaert ML, Farese RV. Beeson M, et al. Among authors: miura a. Diabetes. 2003 Aug;52(8):1926-34. doi: 10.2337/diabetes.52.8.1926. Diabetes. 2003. PMID: 12882907 Clinical Trial.
Increased atypical PKC activity in endurance-trained human skeletal muscle.
Nielsen JN, Frøsig C, Sajan MP, Miura A, Standaert ML, Graham DA, Wojtaszewski JF, Farese RV, Richter EA. Nielsen JN, et al. Among authors: miura a. Biochem Biophys Res Commun. 2003 Dec 26;312(4):1147-53. doi: 10.1016/j.bbrc.2003.11.041. Biochem Biophys Res Commun. 2003. PMID: 14651992 Clinical Trial.
Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.
Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV Jr, Farese RV. Standaert ML, et al. Among authors: miura a. J Biol Chem. 2004 Jun 11;279(24):24929-34. doi: 10.1074/jbc.M402440200. Epub 2004 Apr 6. J Biol Chem. 2004. PMID: 15069067 Free article.
Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance.
Sajan MP, Standaert ML, Rivas J, Miura A, Kanoh Y, Soto J, Taniguchi CM, Kahn CR, Farese RV. Sajan MP, et al. Among authors: miura a. Diabetologia. 2009 Jun;52(6):1197-207. doi: 10.1007/s00125-009-1336-5. Epub 2009 Apr 9. Diabetologia. 2009. PMID: 19357831 Free PMC article.
1,084 results