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Primary Cilium-Mediated Retinal Pigment Epithelium Maturation Is Disrupted in Ciliopathy Patient Cells.
May-Simera HL, Wan Q, Jha BS, Hartford J, Khristov V, Dejene R, Chang J, Patnaik S, Lu Q, Banerjee P, Silver J, Insinna-Kettenhofen C, Patel D, Lotfi M, Malicdan M, Hotaling N, Maminishkis A, Sridharan R, Brooks B, Miyagishima K, Gunay-Aygun M, Pal R, Westlake C, Miller S, Sharma R, Bharti K. May-Simera HL, et al. Among authors: miyagishima k. Cell Rep. 2018 Jan 2;22(1):189-205. doi: 10.1016/j.celrep.2017.12.038. Cell Rep. 2018. PMID: 29298421 Free PMC article.
A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.
Ferrer M, Corneo B, Davis J, Wan Q, Miyagishima KJ, King R, Maminishkis A, Marugan J, Sharma R, Shure M, Temple S, Miller S, Bharti K. Ferrer M, et al. Among authors: miyagishima kj. Stem Cells Transl Med. 2014 Aug;3(8):911-22. doi: 10.5966/sctm.2013-0192. Epub 2014 May 29. Stem Cells Transl Med. 2014. PMID: 24873859 Free PMC article.
In Pursuit of Authenticity: Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Clinical Applications.
Miyagishima KJ, Wan Q, Corneo B, Sharma R, Lotfi MR, Boles NC, Hua F, Maminishkis A, Zhang C, Blenkinsop T, Khristov V, Jha BS, Memon OS, D'Souza S, Temple S, Miller SS, Bharti K. Miyagishima KJ, et al. Stem Cells Transl Med. 2016 Nov;5(11):1562-1574. doi: 10.5966/sctm.2016-0037. Epub 2016 Jul 11. Stem Cells Transl Med. 2016. PMID: 27400791 Free PMC article.
Clinical-grade stem cell-derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs.
Sharma R, Khristov V, Rising A, Jha BS, Dejene R, Hotaling N, Li Y, Stoddard J, Stankewicz C, Wan Q, Zhang C, Campos MM, Miyagishima KJ, McGaughey D, Villasmil R, Mattapallil M, Stanzel B, Qian H, Wong W, Chase L, Charles S, McGill T, Miller S, Maminishkis A, Amaral J, Bharti K. Sharma R, et al. Among authors: miyagishima kj. Sci Transl Med. 2019 Jan 16;11(475):eaat5580. doi: 10.1126/scitranslmed.aat5580. Sci Transl Med. 2019. PMID: 30651323 Free PMC article.
Regulation of phagolysosomal activity by miR-204 critically influences structure and function of retinal pigment epithelium/retina.
Zhang C, Miyagishima KJ, Dong L, Rising A, Nimmagadda M, Liang G, Sharma R, Dejene R, Wang Y, Abu-Asab M, Qian H, Li Y, Kopera M, Maminishkis A, Martinez J, Miller S. Zhang C, et al. Among authors: miyagishima kj. Hum Mol Genet. 2019 Oct 15;28(20):3355-3368. doi: 10.1093/hmg/ddz171. Hum Mol Genet. 2019. PMID: 31332443 Free PMC article.
AMPK modulation ameliorates dominant disease phenotypes of CTRP5 variant in retinal degeneration.
Miyagishima KJ, Sharma R, Nimmagadda M, Clore-Gronenborn K, Qureshy Z, Ortolan D, Bose D, Farnoodian M, Zhang C, Fausey A, Sergeev YV, Abu-Asab M, Jun B, Do KV, Kautzman Guerin MA, Calandria J, George A, Guan B, Wan Q, Sharp RC, Cukras C, Sieving PA, Hufnagel RB, Bazan NG, Boesze-Battaglia K, Miller S, Bharti K. Miyagishima KJ, et al. Commun Biol. 2021 Dec 9;4(1):1360. doi: 10.1038/s42003-021-02872-x. Commun Biol. 2021. PMID: 34887495 Free PMC article.
Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model.
Sharma R, George A, Nimmagadda M, Ortolan D, Karla BS, Qureshy Z, Bose D, Dejene R, Liang G, Wan Q, Chang J, Jha BS, Memon O, Miyagishima KJ, Rising A, Lal M, Hanson E, King R, Campos MM, Ferrer M, Amaral J, McGaughey D, Bharti K. Sharma R, et al. Among authors: miyagishima kj. Nat Commun. 2021 Dec 15;12(1):7293. doi: 10.1038/s41467-021-27488-x. Nat Commun. 2021. PMID: 34911940 Free PMC article.
63 results