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Combined treatment of leukemia cells with vitamin K2 and 1alpha,25-dihydroxy vitamin D3 enhances monocytic differentiation along with becoming resistant to apoptosis by induction of cytoplasmic p21CIP1.
Iguchi T, Miyazawa K, Asada M, Gotoh A, Mizutani S, Ohyashiki K. Iguchi T, et al. Among authors: miyazawa k. Int J Oncol. 2005 Oct;27(4):893-900. Int J Oncol. 2005. PMID: 16142303
[Enhanced sensitivity to cytosine arabinoside by combined stimulation of steel factor and GM-CSF in a factor-dependent leukemic cell line, MO7e--in terms of a possible clinical application to AML treatment].
Gotoh A, Kawanishi Y, Kurosawa K, Miyazawa K, Ohtaka M, Aizawa S, Kimura Y, Yoshikawa O, Toyama K. Gotoh A, et al. Among authors: miyazawa k. Rinsho Ketsueki. 1993 Jul;34(7):821-8. Rinsho Ketsueki. 1993. PMID: 7689660 Japanese.
Vitamin K2 induces apoptosis of a novel cell line established from a patient with myelodysplastic syndrome in blastic transformation.
Nishimaki J, Miyazawa K, Yaguchi M, Katagiri T, Kawanishi Y, Toyama K, Ohyashiki K, Hashimoto S, Nakaya K, Takiguchi T. Nishimaki J, et al. Among authors: miyazawa k. Leukemia. 1999 Sep;13(9):1399-405. doi: 10.1038/sj.leu.2401491. Leukemia. 1999. PMID: 10482991
Comparative multi-color flow cytometric analysis of cell surface antigens in bone marrow hematopoietic progenitors between refractory anemia and aplastic anemia.
Otawa M, Kawanishi Y, Iwase O, Shoji N, Miyazawa K, Ohyashiki K. Otawa M, et al. Among authors: miyazawa k. Leuk Res. 2000 Apr;24(4):359-66. doi: 10.1016/s0145-2126(99)00194-0. Leuk Res. 2000. PMID: 10713334
Megakaryocytic Maturation is Regulated by Maintaining a Balance Against Cytokine Induced-cell Proliferation: Steel Factor Retards Thrombopoietin-induced Megakaryocytic Differentiation While Synergistically Stimulating Mitogenesis; Hematopoiesis.
Miyazawa K, Nishimaki J, Katagiri T, Yaguchi M, Iwase O, Gotoh A, Tauchi T, Kawanishi Y, Toyama K, Ohyashiki K, Ishibashi T, Broxmeyer HE. Miyazawa K, et al. Hematology. 2000;5(3):233-246. doi: 10.1080/10245332.2000.11746512. Hematology. 2000. PMID: 11399618
Apoptosis/differentiation-inducing effects of vitamin K2 on HL-60 cells: dichotomous nature of vitamin K2 in leukemia cells.
Miyazawa K, Yaguchi M, Funato K, Gotoh A, Kawanishi Y, Nishizawa Y, Yuo A, Ohyashiki K. Miyazawa K, et al. Leukemia. 2001 Jul;15(7):1111-7. doi: 10.1038/sj.leu.2402155. Leukemia. 2001. PMID: 11455981
Re-evaluation of refractory anemia with excess blasts in transformation.
Ohyashiki K, Nishimaki J, Shoji N, Miyazawa K, Kimura Y, Ohyashiki JH. Ohyashiki K, et al. Among authors: miyazawa k. Leuk Res. 2001 Nov;25(11):933-9. doi: 10.1016/s0145-2126(01)00054-6. Leuk Res. 2001. PMID: 11597728
Bone marrow cytogenetic complete remission achieved by interferon-alpha plus cytarabine ocfosfate therapy in a patient with chronic myelogenous leukemia during extramedullary blast crisis.
Gotoh A, Miyazawa K, Uchida Y, Sashida G, Kawakubo K, Kuriyama Y, Ohyashiki K. Gotoh A, et al. Among authors: miyazawa k. Int J Hematol. 2002 Feb;75(2):191-4. doi: 10.1007/BF02982027. Int J Hematol. 2002. PMID: 11939268
Changes in N-glycosylation of human stromal cells by telomerase expression.
Kuwahara I, Ikebuchi K, Hamada H, Niitsu Y, Miyazawa K, Ohyashiki K, Fujisawa H, Furukawa K. Kuwahara I, et al. Among authors: miyazawa k. Biochem Biophys Res Commun. 2003 Feb 7;301(2):293-7. doi: 10.1016/s0006-291x(02)03032-2. Biochem Biophys Res Commun. 2003. PMID: 12565858
Can eradication therapy for Helicobacter pylori really improve the thrombocytopenia in idiopathic thrombocytopenic purpura? Our experience and a literature review.
Ando K, Shimamoto T, Tauchi T, Ito Y, Kuriyama Y, Gotoh A, Miyazawa K, Kimura Y, Kawai T, Ohyashiki K. Ando K, et al. Among authors: miyazawa k. Int J Hematol. 2003 Apr;77(3):239-44. doi: 10.1007/BF02983780. Int J Hematol. 2003. PMID: 12731666 Clinical Trial.
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