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Thioxothiazolidin derivative, 4-OST, inhibits melanogenesis by enhancing the specific recruitment of tyrosinase-containing vesicles to lysosome.
Isogawa K, Asano M, Hayazaki M, Koga K, Watanabe M, Suzuki K, Kobayashi T, Kawaguchi K, Ishizuka A, Kato S, Ito H, Hamamoto A, Koyama H, Furuta K, Takemori H. Isogawa K, et al. Among authors: watanabe m. J Cell Biochem. 2021 Jun;122(6):667-678. doi: 10.1002/jcb.29895. Epub 2021 Jan 22. J Cell Biochem. 2021. PMID: 33480093
Identification of novel neuroprotective N,N-dimethylaniline derivatives that prevent oxytosis/ferroptosis and localize to late endosomes and lysosomes.
Hirata Y, Tsunekawa Y, Takahashi M, Oh-Hashi K, Kawaguchi K, Hayazaki M, Watanabe M, Koga KI, Hattori Y, Takemori H, Furuta K. Hirata Y, et al. Among authors: watanabe m. Free Radic Biol Med. 2021 Oct;174:225-235. doi: 10.1016/j.freeradbiomed.2021.08.015. Epub 2021 Aug 15. Free Radic Biol Med. 2021. PMID: 34407426