Significant improvement of mouse cloning technique by treatment with trichostatin A after somatic nuclear transfer.
Kishigami S, Mizutani E, Ohta H, Hikichi T, Thuan NV, Wakayama S, Bui HT, Wakayama T.
Kishigami S, et al. Among authors: mizutani e.
Biochem Biophys Res Commun. 2006 Feb 3;340(1):183-9. doi: 10.1016/j.bbrc.2005.11.164. Epub 2005 Dec 9.
Biochem Biophys Res Commun. 2006.
PMID: 16356478
Recently, we elucidated by using round spermatids that, after nuclear transfer, treatment of zygotes with trichostatin A (TSA), an inhibitor of histone deacetylase, can remarkably reduce abnormal DNA hypermethylation depending on the origins of transferred nuclei and their genomi …
Recently, we elucidated by using round spermatids that, after nuclear transfer, treatment of zygotes with trichostatin A (TSA), an inhibitor …