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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
1998 1
2003 2
2004 5
2005 7
2006 11
2007 13
2008 13
2009 23
2010 23
2011 27
2012 35
2013 47
2014 48
2015 37
2016 52
2017 69
2018 170
2019 235
2020 252
2021 205
2022 135
2023 109
2024 37

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1,335 results

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Page 1
Breast cancer.
Loibl S, Poortmans P, Morrow M, Denkert C, Curigliano G. Loibl S, et al. Lancet. 2021 May 8;397(10286):1750-1769. doi: 10.1016/S0140-6736(20)32381-3. Epub 2021 Apr 1. Lancet. 2021. PMID: 33812473 Review.
But the way breast cancer is viewed has changed drastically since its molecular hallmarks were extensively characterised, now including immunohistochemical markers (eg, ER, PR, HER2 [ERBB2], and proliferation marker protein Ki-67 [MKI67]), genomic markers (eg, BRCA1, BRCA2 …
But the way breast cancer is viewed has changed drastically since its molecular hallmarks were extensively characterised, now including immu …
MKI67 as a potential diagnostic biomarker in pulmonary hypertension.
Zhou H, Gong K, Yang Y, Wu Q, Wang Q, Shen Y, Xie L, Gong Y, Liu H, Liu J. Zhou H, et al. Front Pediatr. 2022 Nov 1;10:1016889. doi: 10.3389/fped.2022.1016889. eCollection 2022. Front Pediatr. 2022. PMID: 36389368 Free PMC article.
After suppressing MKI67 in PASMCs, both cell proliferation and migration decreased. ...This implies that PH can be diagnosed and treated using MKI67....
After suppressing MKI67 in PASMCs, both cell proliferation and migration decreased. ...This implies that PH can be diagnosed and trea …
Correlation of MKI67 with prognosis, immune infiltration, and T cell exhaustion in hepatocellular carcinoma.
Wu SY, Liao P, Yan LY, Zhao QY, Xie ZY, Dong J, Sun HT. Wu SY, et al. BMC Gastroenterol. 2021 Nov 1;21(1):416. doi: 10.1186/s12876-021-01984-2. BMC Gastroenterol. 2021. PMID: 34724892 Free PMC article.
BACKGROUND: MKI67 plays a vital role in the tumour microenvironment (TME) and congenital immunity. ...Detection of the MKI67 level contributes to prognosis prediction and MKI67 modulation within exhausted T cells, thus providing a new method to optimize the e …
BACKGROUND: MKI67 plays a vital role in the tumour microenvironment (TME) and congenital immunity. ...Detection of the MKI67 l …
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis.
Guttman-Yassky E, Bissonnette R, Ungar B, Suárez-Fariñas M, Ardeleanu M, Esaki H, Suprun M, Estrada Y, Xu H, Peng X, Silverberg JI, Menter A, Krueger JG, Zhang R, Chaudhry U, Swanson B, Graham NMH, Pirozzi G, Yancopoulos GD, D Hamilton JD. Guttman-Yassky E, et al. J Allergy Clin Immunol. 2019 Jan;143(1):155-172. doi: 10.1016/j.jaci.2018.08.022. Epub 2018 Sep 5. J Allergy Clin Immunol. 2019. PMID: 30194992 Free article. Clinical Trial.
Dupilumab significantly reduced expression of genes involved in type 2 inflammation (IL13, IL31, CCL17, CCL18, and CCL26), epidermal hyperplasia (keratin 16 [K16] and MKi67), T cells, dendritic cells (ICOS, CD11c, and CTLA4), and T(H)17/T(H)22 activity (IL17A, IL-22, and S …
Dupilumab significantly reduced expression of genes involved in type 2 inflammation (IL13, IL31, CCL17, CCL18, and CCL26), epidermal hyperpl …
MKI67 an potential oncogene of oral squamous cell carcinoma via the high throughput technology.
Liu ZM, Bao Y, Li TK, Di YB, Song WJ. Liu ZM, et al. Medicine (Baltimore). 2022 Dec 30;101(52):e32595. doi: 10.1097/MD.0000000000032595. Medicine (Baltimore). 2022. PMID: 36596059 Free PMC article.
Oral squamous cell carcinoma is a malignant tumor that occurs in the oral cavity, with poor prognosis and easy recurrence. However, the relationship between MKI67 and oral squamous cell carcinoma remains unclear. The oral squamous cell carcinoma datasets GSE138206, GSE1464 …
Oral squamous cell carcinoma is a malignant tumor that occurs in the oral cavity, with poor prognosis and easy recurrence. However, the rela …
STMN1 and MKI67 Are Upregulated in Uterine Leiomyosarcoma and Are Potential Biomarkers for its Diagnosis.
Hu X, Zhang H, Zheng X, Lin Z, Feng G, Chen Y, Pan Q, Ni F. Hu X, et al. Med Sci Monit. 2020 May 19;26:e923749. doi: 10.12659/MSM.923749. Med Sci Monit. 2020. PMID: 32425177 Free PMC article.
BACKGROUND The aim of this study was to investigate STMN1 and MKI67 expression in uterine leiomyosarcoma and their potential roles as biomarkers for diagnosis. MATERIAL AND METHODS The expression of STMN1 and MKI67 mRNA in uterine leiomyosarcoma were investigated in …
BACKGROUND The aim of this study was to investigate STMN1 and MKI67 expression in uterine leiomyosarcoma and their potential roles as …
Single-cell transcriptomics reveals cellular heterogeneity and molecular stratification of cervical cancer.
Li C, Wu H, Guo L, Liu D, Yang S, Li S, Hua K. Li C, et al. Commun Biol. 2022 Nov 10;5(1):1208. doi: 10.1038/s42003-022-04142-w. Commun Biol. 2022. PMID: 36357663 Free PMC article.
We also identified cancer-associated fibroblasts (CAFs) that may promote tumor progression of CC, and further distinguished inflammatory CAF (iCAF) and myofibroblastic CAF (myCAF). CD8(+) T cell diversity revealed both proliferative (MKI67(+)) and non-cycling exhausted (PD …
We also identified cancer-associated fibroblasts (CAFs) that may promote tumor progression of CC, and further distinguished inflammatory CAF …
Single-cell transcriptomic analysis reveals disparate effector differentiation pathways in human Treg compartment.
Luo Y, Xu C, Wang B, Niu Q, Su X, Bai Y, Zhu S, Zhao C, Sun Y, Wang J, Liu M, Sun X, Song G, Cui H, Chen X, Huang H, Wang H, Han M, Jiang E, Shi L, Feng X. Luo Y, et al. Nat Commun. 2021 Jun 23;12(1):3913. doi: 10.1038/s41467-021-24213-6. Nat Commun. 2021. PMID: 34162888 Free PMC article.
These analyses, combined with functional assays, separate T(reg) cells into naive, activated, and effector stages, and resolve the HLA-DR(hi), LIMS1(hi), highly suppressive FOXP3(hi), and highly proliferative MKI67(hi) effector subsets. Trajectory analysis assembles T(reg) …
These analyses, combined with functional assays, separate T(reg) cells into naive, activated, and effector stages, and resolve the HLA-DR(hi …
Novel CH25H+ and OASL+ microglia subclusters play distinct roles in cerebral ischemic stroke.
Zhang Y, Guo Y, Li R, Huang T, Li Y, Xie W, Chen C, Chen W, Wan J, Yu W, Li P. Zhang Y, et al. J Neuroinflammation. 2023 May 15;20(1):115. doi: 10.1186/s12974-023-02799-6. J Neuroinflammation. 2023. PMID: 37183260 Free PMC article.
RESULTS: We identified a relatively homeostatic subcluster with enhanced antigen processing and three "ischemic stroke associated microglia" (ISAM): MKI67(+), CH25H(+) and OASL(+) subclusters. We found the MKI67(+) subcluster undergo proliferation and differentiatio …
RESULTS: We identified a relatively homeostatic subcluster with enhanced antigen processing and three "ischemic stroke associated microglia" …
1,335 results