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Page 1
Lack of CCM1 induces hypersprouting and impairs response to flow.
Mleynek TM, Chan AC, Redd M, Gibson CC, Davis CT, Shi DS, Chen T, Carter KL, Ling J, Blanco R, Gerhardt H, Whitehead K, Li DY. Mleynek TM, et al. Hum Mol Genet. 2014 Dec 1;23(23):6223-34. doi: 10.1093/hmg/ddu342. Epub 2014 Jul 2. Hum Mol Genet. 2014. PMID: 24990152 Free PMC article.
Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy.
Zhu W, Shi DS, Winter JM, Rich BE, Tong Z, Sorensen LK, Zhao H, Huang Y, Tai Z, Mleynek TM, Yoo JH, Dunn C, Ling J, Bergquist JA, Richards JR, Jiang A, Lesniewski LA, Hartnett ME, Ward DM, Mueller AL, Ostanin K, Thomas KR, Odelberg SJ, Li DY. Zhu W, et al. Among authors: mleynek tm. J Clin Invest. 2017 Dec 1;127(12):4569-4582. doi: 10.1172/JCI91770. Epub 2017 Oct 23. J Clin Invest. 2017. PMID: 29058688 Free PMC article.
ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma.
Yoo JH, Shi DS, Grossmann AH, Sorensen LK, Tong Z, Mleynek TM, Rogers A, Zhu W, Richards JR, Winter JM, Zhu J, Dunn C, Bajji A, Shenderovich M, Mueller AL, Woodman SE, Harbour JW, Thomas KR, Odelberg SJ, Ostanin K, Li DY. Yoo JH, et al. Among authors: mleynek tm. Cancer Cell. 2016 Jun 13;29(6):889-904. doi: 10.1016/j.ccell.2016.04.015. Epub 2016 Jun 2. Cancer Cell. 2016. PMID: 27265506 Free PMC article.
The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.
Yoo JH, Brady SW, Acosta-Alvarez L, Rogers A, Peng J, Sorensen LK, Wolff RK, Mleynek T, Shin D, Rich CP, Kircher DA, Bild A, Odelberg SJ, Li DY, Holmen SL, Grossmann AH. Yoo JH, et al. Cancer Res. 2019 Jun 1;79(11):2892-2908. doi: 10.1158/0008-5472.CAN-18-3026. Epub 2019 May 2. Cancer Res. 2019. PMID: 31048499 Free PMC article.