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Targeting the function of the HER2 oncogene in human cancer therapeutics.
Moasser MM. Moasser MM. Oncogene. 2007 Oct 11;26(46):6577-92. doi: 10.1038/sj.onc.1210478. Epub 2007 May 7. Oncogene. 2007. PMID: 17486079 Free PMC article. Review.
Growth suppression of acute promyelocytic leukemia cells having increased expression of the non-rearranged alleles: RAR alpha or PML.
Ahn MJ, Nason-Burchenal K, Moasser MM, Dmitrovsky E. Ahn MJ, et al. Among authors: moasser mm. Oncogene. 1995 Jun 15;10(12):2307-14. Oncogene. 1995. PMID: 7784078
Response and resistance to retinoic acid are mediated through the retinoic acid nuclear receptor gamma in human teratocarcinomas.
Moasser MM, DeBlasio A, Dmitrovsky E. Moasser MM, et al. Oncogene. 1994 Mar;9(3):833-40. Oncogene. 1994. PMID: 8108126
Growth suppression of transformed human bronchial epithelial cells by all-trans-retinoic acid occurs through specific retinoid receptors.
Ahn MJ, Langenfeld J, Moasser MM, Rusch V, Dmitrovsky E. Ahn MJ, et al. Among authors: moasser mm. Oncogene. 1995 Dec 7;11(11):2357-64. Oncogene. 1995. PMID: 8570187
Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification.
Seidman AD, Fornier MN, Esteva FJ, Tan L, Kaptain S, Bach A, Panageas KS, Arroyo C, Valero V, Currie V, Gilewski T, Theodoulou M, Moynahan ME, Moasser M, Sklarin N, Dickler M, D'Andrea G, Cristofanilli M, Rivera E, Hortobagyi GN, Norton L, Hudis CA. Seidman AD, et al. J Clin Oncol. 2001 May 15;19(10):2587-95. doi: 10.1200/JCO.2001.19.10.2587. J Clin Oncol. 2001. PMID: 11352950 Clinical Trial.
The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells.
Moasser MM, Basso A, Averbuch SD, Rosen N. Moasser MM, et al. Cancer Res. 2001 Oct 1;61(19):7184-8. Cancer Res. 2001. PMID: 11585753
Phase II study of celecoxib and trastuzumab in metastatic breast cancer patients who have progressed after prior trastuzumab-based treatments.
Dang CT, Dannenberg AJ, Subbaramaiah K, Dickler MN, Moasser MM, Seidman AD, D'Andrea GM, Theodoulou M, Panageas KS, Norton L, Hudis CA. Dang CT, et al. Among authors: moasser mm. Clin Cancer Res. 2004 Jun 15;10(12 Pt 1):4062-7. doi: 10.1158/1078-0432.CCR-03-0463. Clin Cancer Res. 2004. PMID: 15217939 Clinical Trial.
Adhesion signaling by a novel mitotic substrate of src kinases.
Bhatt AS, Erdjument-Bromage H, Tempst P, Craik CS, Moasser MM. Bhatt AS, et al. Among authors: moasser mm. Oncogene. 2005 Aug 11;24(34):5333-43. doi: 10.1038/sj.onc.1208582. Oncogene. 2005. PMID: 16007225 Free PMC article.
Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3.
Sergina NV, Rausch M, Wang D, Blair J, Hann B, Shokat KM, Moasser MM. Sergina NV, et al. Among authors: moasser mm. Nature. 2007 Jan 25;445(7126):437-41. doi: 10.1038/nature05474. Epub 2007 Jan 7. Nature. 2007. PMID: 17206155 Free PMC article.
The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis.
Moasser MM. Moasser MM. Oncogene. 2007 Oct 4;26(45):6469-87. doi: 10.1038/sj.onc.1210477. Epub 2007 Apr 30. Oncogene. 2007. PMID: 17471238 Free PMC article. Review.
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