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The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism.
Wootten D, Reynolds CA, Smith KJ, Mobarec JC, Koole C, Savage EE, Pabreja K, Simms J, Sridhar R, Furness SGB, Liu M, Thompson PE, Miller LJ, Christopoulos A, Sexton PM. Wootten D, et al. Among authors: mobarec jc. Cell. 2016 Jun 16;165(7):1632-1643. doi: 10.1016/j.cell.2016.05.023. Cell. 2016. PMID: 27315480 Free PMC article.
Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors.
Weston C, Winfield I, Harris M, Hodgson R, Shah A, Dowell SJ, Mobarec JC, Woodlock DA, Reynolds CA, Poyner DR, Watkins HA, Ladds G. Weston C, et al. Among authors: mobarec jc. J Biol Chem. 2016 Oct 14;291(42):21925-21944. doi: 10.1074/jbc.M116.751362. Epub 2016 Aug 26. J Biol Chem. 2016. PMID: 27566546 Free PMC article.
Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors.
Weston C, Winfield I, Harris M, Hodgson R, Shah A, Dowell SJ, Mobarec JC, Woodcock DA, Reynolds CA, Poyner DR, Watkins HA, Ladds G. Weston C, et al. Among authors: mobarec jc. J Biol Chem. 2016 Dec 2;291(49):25763. doi: 10.1074/jbc.A116.751362. J Biol Chem. 2016. PMID: 27913664 Free PMC article. No abstract available.
Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs.
Woolley MJ, Reynolds CA, Simms J, Walker CS, Mobarec JC, Garelja ML, Conner AC, Poyner DR, Hay DL. Woolley MJ, et al. Among authors: mobarec jc. Biochem Pharmacol. 2017 Oct 15;142:96-110. doi: 10.1016/j.bcp.2017.07.005. Epub 2017 Jul 11. Biochem Pharmacol. 2017. PMID: 28705698 Free PMC article.
23 results