Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

277 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment.
Buhrmann C, Mobasheri A, Matis U, Shakibaei M. Buhrmann C, et al. Arthritis Res Ther. 2010;12(4):R127. doi: 10.1186/ar3065. Epub 2010 Jul 1. Arthritis Res Ther. 2010. PMID: 20594343 Free PMC article.
Curcumin is a phytochemical capable of inhibiting IL-1β-induced activation of NF-κB and expression of apoptotic and pro-inflammatory genes in chondrocytes. ...METHODS: MSCs were either cultured in a ratio of 1:1 with primary chondrocytes in high-density culture or c …
Curcumin is a phytochemical capable of inhibiting IL-1β-induced activation of NF-κB and expression of apoptotic and pro-inflammatory …
Expression of the VEGF receptor-3 in osteoarthritic chondrocytes: stimulation by interleukin-1 beta and association with beta 1-integrins.
Shakibaei M, Schulze-Tanzil G, Mobasheri A, Beichler T, Dressler J, Schwab W. Shakibaei M, et al. Histochem Cell Biol. 2003 Sep;120(3):235-41. doi: 10.1007/s00418-003-0558-8. Epub 2003 Aug 2. Histochem Cell Biol. 2003. PMID: 12904969
Using western blotting we could demonstrate that interleukin-1 beta (IL-1 beta) stimulates the expression of VEGFR-3 in chondrocytes in vitro in a dose-dependent manner. By coimmunoprecipitation assay we found a functional complex between the beta(1)-integrin and VE …
Using western blotting we could demonstrate that interleukin-1 beta (IL-1 beta) stimulates the expression of VEGFR-3 in chondrocytes in vitr …
Interleukin-1beta-induced expression of the urokinase-type plasminogen activator receptor and its co-localization with MMPs in human articular chondrocytes.
Schwab W, Schulze-Tanzil G, Mobasheri A, Dressler J, Kotzsch M, Shakibaei M. Schwab W, et al. Histol Histopathol. 2004 Jan;19(1):105-12. doi: 10.14670/HH-19.105. Histol Histopathol. 2004. PMID: 14702177
MMPs are regulated by IL-1beta, a cytokine that plays a pivotal role in pathogenesis of osteoarthritis. This study was undertaken to address two questions: 1. ...Furthermore, we found a functional co-localization between uPAR and MMP-9 on IL-1beta-stimulated …
MMPs are regulated by IL-1beta, a cytokine that plays a pivotal role in pathogenesis of osteoarthritis. This study was underta …
Loss of chondrogenic potential in dedifferentiated chondrocytes correlates with deficient Shc-Erk interaction and apoptosis.
Schulze-Tanzil G, Mobasheri A, de Souza P, John T, Shakibaei M. Schulze-Tanzil G, et al. Osteoarthritis Cartilage. 2004 Jun;12(6):448-58. doi: 10.1016/j.joca.2004.02.007. Osteoarthritis Cartilage. 2004. PMID: 15135141
METHODS: Human chondrocytes that had migrated from alginate beads to form a monolayer (passage 1) were passaged seven times (passages 2-8). ...A decrease in Shc/Erk expression/interaction could serve as a recognition marker for irreversibly dedifferentiated c …
METHODS: Human chondrocytes that had migrated from alginate beads to form a monolayer (passage 1) were passaged seven times (passages …
Cultivation of human tenocytes in high-density culture.
Schulze-Tanzil G, Mobasheri A, Clegg PD, Sendzik J, John T, Shakibaei M. Schulze-Tanzil G, et al. Histochem Cell Biol. 2004 Sep;122(3):219-28. doi: 10.1007/s00418-004-0694-9. Epub 2004 Aug 27. Histochem Cell Biol. 2004. PMID: 15338228
In this study we established a three-dimensional high-density culture system for cultivation of human tenocytes for tissue engineering. ...Differentiated tenocytes were able to survive over a period of 14 days in high-density culture. During the culture period tenoc …
In this study we established a three-dimensional high-density culture system for cultivation of human tenocytes for tissue engineerin …
Effects of curcumin (diferuloylmethane) on nuclear factor kappaB signaling in interleukin-1beta-stimulated chondrocytes.
Schulze-Tanzil G, Mobasheri A, Sendzik J, John T, Shakibaei M. Schulze-Tanzil G, et al. Ann N Y Acad Sci. 2004 Dec;1030:578-86. doi: 10.1196/annals.1329.067. Ann N Y Acad Sci. 2004. PMID: 15659840
Curcumin (diferuloylmethane) is a nontoxic dietary pigment in tumeric and curry and a potent inhibitor of the common transcription factor Nuclear Factor kappaB (NF-kappaB) in several cell types. ...IL-1beta induced a decrease in collagen type II and upregulat …
Curcumin (diferuloylmethane) is a nontoxic dietary pigment in tumeric and curry and a potent inhibitor of the common transcrip …
Curcumin protects human chondrocytes from IL-l1beta-induced inhibition of collagen type II and beta1-integrin expression and activation of caspase-3: an immunomorphological study.
Shakibaei M, Schulze-Tanzil G, John T, Mobasheri A. Shakibaei M, et al. Ann Anat. 2005 Nov;187(5-6):487-97. doi: 10.1016/j.aanat.2005.06.007. Ann Anat. 2005. PMID: 16320828
Interleukin 1beta (IL-1beta) is a pleiotropic pro-inflammatory cytokine that plays a key role in mediating cartilage degradation in osteoarticular disorders such as osteoarthritis (OA) and rheumatoid arthritis (RA). ...Additionally, curcumin antagonized IL-1beta-ind …
Interleukin 1beta (IL-1beta) is a pleiotropic pro-inflammatory cytokine that plays a key role in mediating cartilage degradati …
Igf-I extends the chondrogenic potential of human articular chondrocytes in vitro: molecular association between Sox9 and Erk1/2.
Shakibaei M, Seifarth C, John T, Rahmanzadeh M, Mobasheri A. Shakibaei M, et al. Biochem Pharmacol. 2006 Nov 30;72(11):1382-95. doi: 10.1016/j.bcp.2006.08.022. Epub 2006 Sep 29. Biochem Pharmacol. 2006. PMID: 17010943
Dedifferentiation of chondrocytes in monolayer culture is a challenging problem for autologous chondrocyte transplantation (ACT). ...Immunoprecipitation revealed that phosphorylated Erk1/2 physically interacts with Sox9 in chondrocyte nuclei, suggesting a previously …
Dedifferentiation of chondrocytes in monolayer culture is a challenging problem for autologous chondrocyte transplantation (ACT). ... …
Suppression of NF-kappaB activation by curcumin leads to inhibition of expression of cyclo-oxygenase-2 and matrix metalloproteinase-9 in human articular chondrocytes: Implications for the treatment of osteoarthritis.
Shakibaei M, John T, Schulze-Tanzil G, Lehmann I, Mobasheri A. Shakibaei M, et al. Biochem Pharmacol. 2007 May 1;73(9):1434-45. doi: 10.1016/j.bcp.2007.01.005. Epub 2007 Jan 7. Biochem Pharmacol. 2007. PMID: 17291458
Pro-inflammatory cytokines such as interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) play a key role in the pathogenesis of osteoarthritis (OA). Anti-inflammatory agents capable of suppressing the production and catabolic actions of these cytokines m …
Pro-inflammatory cytokines such as interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) play a key role in the pa …
Resveratrol inhibits IL-1 beta-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro.
Shakibaei M, John T, Seifarth C, Mobasheri A. Shakibaei M, et al. Ann N Y Acad Sci. 2007 Jan;1095:554-63. doi: 10.1196/annals.1397.060. Ann N Y Acad Sci. 2007. PMID: 17404069
The pro-inflammatory cytokine interleukin-1beta (IL-1beta) plays a pivotal role in the pathogenesis of osteoarthritis (OA) in humans and animals. ...Resveratrol significantly reduced the IL-1beta-induced inhibition of expression of cartilage-specific collagen type II and s …
The pro-inflammatory cytokine interleukin-1beta (IL-1beta) plays a pivotal role in the pathogenesis of osteoarthritis (OA) in humans …
277 results
Jump to page
Feedback