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Mobile elements contribute to the uniqueness of human genome with 15,000 human-specific insertions and 14 Mbp sequence increase.
Tang W, Mun S, Joshi A, Han K, Liang P. Tang W, et al. DNA Res. 2018 Oct 1;25(5):521-533. doi: 10.1093/dnares/dsy022. DNA Res. 2018. PMID: 30052927 Free PMC article.
Mobile elements (MEs) collectively contribute to at least 50% of the human genome. ...In conclusion, our results demonstrate that MEs made a significant contribution to the evolution of human genome by participating in gene function in a
Mobile elements (MEs) collectively contribute to at least 50% of the human genome. ...In conclusion, our results
Retroelement-derived RNA and its role in the brain.
Evans TA, Erwin JA. Evans TA, et al. Semin Cell Dev Biol. 2021 Jun;114:68-80. doi: 10.1016/j.semcdb.2020.11.001. Epub 2020 Nov 21. Semin Cell Dev Biol. 2021. PMID: 33229216 Review.
Comprising ~40% of the human genome, retroelements are mobile genetic elements which are transcribed into RNA, then reverse-transcribed into DNA and inserted into a new site in the genome. ...In humans, an increasing number of neurodevelopmental and ne …
Comprising ~40% of the human genome, retroelements are mobile genetic elements which are transcribed into RNA, then rev …
Antibiotic resistance in Vibrio cholerae: Understanding the ecology of resistance genes and mechanisms.
Das B, Verma J, Kumar P, Ghosh A, Ramamurthy T. Das B, et al. Vaccine. 2020 Feb 29;38 Suppl 1:A83-A92. doi: 10.1016/j.vaccine.2019.06.031. Epub 2019 Jul 2. Vaccine. 2020. PMID: 31272870 Free article. Review.
In the last few decades, V. cholerae that causes acute watery diarrhoeal disease cholera has emerged as a notorious multidrug resistant (MDR) enteric pathogen. Although chromosomal mutations can contribute to antimicrobial resistance (AMR), the frequent acquisition of extr …
In the last few decades, V. cholerae that causes acute watery diarrhoeal disease cholera has emerged as a notorious multidrug resistant (MDR …
Analysis of RNA-Seq Data Using TEtranscripts.
Jin Y, Hammell M. Jin Y, et al. Methods Mol Biol. 2018;1751:153-167. doi: 10.1007/978-1-4939-7710-9_11. Methods Mol Biol. 2018. PMID: 29508296
Transposable elements (TE) are mobile genetic elements that can readily change their genomic position. When not properly silenced, TEs can contribute a substantial portion to the cell's transcriptome, but are typically ignored in most RNA-seq da …
Transposable elements (TE) are mobile genetic elements that can readily change their genomic position. When not properl …
Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus.
Diep BA, Gill SR, Chang RF, Phan TH, Chen JH, Davidson MG, Lin F, Lin J, Carleton HA, Mongodin EF, Sensabaugh GF, Perdreau-Remington F. Diep BA, et al. Lancet. 2006 Mar 4;367(9512):731-9. doi: 10.1016/S0140-6736(06)68231-7. Lancet. 2006. PMID: 16517273 Review.
We did not detect this element, termed arginine catabolic mobile element (ACME), in other S aureus strains. We noted a high prevalence of ACME in S epidermidis, suggesting not only that ACME transfers into USA300 from S epidermidis, but a …
We did not detect this element, termed arginine catabolic mobile element (ACME), in other S aureus strains. We n …
The dissemination of C10 cysteine protease genes in Bacteroides fragilis by mobile genetic elements.
Thornton RF, Kagawa TF, O'Toole PW, Cooney JC. Thornton RF, et al. BMC Microbiol. 2010 Apr 23;10:122. doi: 10.1186/1471-2180-10-122. BMC Microbiol. 2010. PMID: 20416045 Free PMC article.
The presence of homologues of cysteine protease genes in human commensal organisms has not been examined. Bacteroides fragilis is a member of the dominant Bacteroidetes phylum of the human intestinal microbiota, and is a significant opportunistic pathogen. ...Gene a …
The presence of homologues of cysteine protease genes in human commensal organisms has not been examined. Bacteroides fragilis is a m …
Functional modularity of the arginine catabolic mobile element contributes to the success of USA300 methicillin-resistant Staphylococcus aureus.
Thurlow LR, Joshi GS, Clark JR, Spontak JS, Neely CJ, Maile R, Richardson AR. Thurlow LR, et al. Cell Host Microbe. 2013 Jan 16;13(1):100-7. doi: 10.1016/j.chom.2012.11.012. Epub 2013 Jan 16. Cell Host Microbe. 2013. PMID: 23332159 Free PMC article.
The USA300 community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage causes the majority of skin and soft tissue infections (SSTIs) and is highly associated with the carriage of the arginine catabolic mobile element (ACME). However, the c
The USA300 community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage causes the majority of skin and soft tissue in …
Use of mobile phones for behavior change communication to improve maternal, newborn and child health: a scoping review.
Mildon A, Sellen D. Mildon A, et al. J Glob Health. 2019 Dec;9(2):020425. doi: 10.7189/jogh.09.020425. J Glob Health. 2019. PMID: 31893032 Free PMC article. Review.
These elements influence resource allocation and are likely to impact effectiveness for BCC targeting complex, habitual MNCH practices. CONCLUSIONS: This scoping review contributes to the evidence-base on the opportunities and limitations of using mobile phon …
These elements influence resource allocation and are likely to impact effectiveness for BCC targeting complex, habitual MNCH practice …
Diversity of P1 phage-like elements in multidrug resistant Escherichia coli.
Venturini C, Zingali T, Wyrsch ER, Bowring B, Iredell J, Partridge SR, Djordjevic SP. Venturini C, et al. Sci Rep. 2019 Dec 11;9(1):18861. doi: 10.1038/s41598-019-54895-4. Sci Rep. 2019. PMID: 31827120 Free PMC article.
The spread of multidrug resistance via mobile genetic elements is a major clinical and veterinary concern. ...All three elements are coliphage P1 variants, each with unique adaptations. pJIE250-3 is a P1-derivative that has lost lytic functions and con …
The spread of multidrug resistance via mobile genetic elements is a major clinical and veterinary concern. ...All three ele
Bacteriophages in the human gut: Our fellow travelers throughout life and potential biomarkers of heath or disease.
Bakhshinejad B, Ghiasvand S. Bakhshinejad B, et al. Virus Res. 2017 Aug 15;240:47-55. doi: 10.1016/j.virusres.2017.07.013. Epub 2017 Jul 22. Virus Res. 2017. PMID: 28743462 Review.
Phageome seems to be unique to each individual and shows a high degree of interpersonal variation. In the healthy gut, a vast majority of phages have a lysogenic lifestyle. These prophages serve as a major respository of mobile genetic elements in the gut and …
Phageome seems to be unique to each individual and shows a high degree of interpersonal variation. In the healthy gut, a vast majorit …
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