Mochizuki-Kashio M - Search Results

1

Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation.

Sashida G, Harada H, Matsui H, Oshima M, Yui M, Harada Y, Tanaka S, Mochizuki-Kashio M, Wang C, Saraya A, Muto T, Hayashi Y, Suzuki K, Nakajima H, Inaba T, Koseki H, Huang G, Kitamura T, Iwama A. Sashida G, et al. Nat Commun. 2014 Jun 23;5:4177. doi: 10.1038/ncomms5177. Nat Commun. 2014. PMID: 24953053 Free article.

2

Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic stem cells.

Konuma T, Nakamura S, Miyagi S, Negishi M, Chiba T, Oguro H, Yuan J, Mochizuki-Kashio M, Ichikawa H, Miyoshi H, Vidal M, Iwama A. Konuma T, et al. Exp Hematol. 2011 Jun;39(6):697-709.e5. doi: 10.1016/j.exphem.2011.03.008. Epub 2011 Apr 12. Exp Hematol. 2011. PMID: 21540074 Free article.

3

Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase.

Nishino T, Wang C, Mochizuki-Kashio M, Osawa M, Nakauchi H, Iwama A. Nishino T, et al. PLoS One. 2011;6(9):e24298. doi: 10.1371/journal.pone.0024298. Epub 2011 Sep 12. PLoS One. 2011. PMID: 21931675 Free PMC article.

4

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells.

Mochizuki-Kashio M, Mishima Y, Miyagi S, Negishi M, Saraya A, Konuma T, Shinga J, Koseki H, Iwama A. Mochizuki-Kashio M, et al. Blood. 2011 Dec 15;118(25):6553-61. doi: 10.1182/blood-2011-03-340554. Epub 2011 Oct 31. Blood. 2011. PMID: 22042701 Free article.

5

Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes.

Oguro H, Yuan J, Tanaka S, Miyagi S, Mochizuki-Kashio M, Ichikawa H, Yamazaki S, Koseki H, Nakauchi H, Iwama A. Oguro H, et al. J Exp Med. 2012 Mar 12;209(3):445-54. doi: 10.1084/jem.20111709. Epub 2012 Feb 20. J Exp Med. 2012. PMID: 22351929 Free PMC article.

6

Tumor suppressor function of the polycomb group genes.

Mochizuki-Kashio M, Wendt GR, Iwama A. Mochizuki-Kashio M, et al. Cell Cycle. 2012 Jun 1;11(11):2043-4. doi: 10.4161/cc.20533. Epub 2012 Jun 1. Cell Cycle. 2012. PMID: 22592526 No abstract available.

7

Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia.

Tanaka S, Miyagi S, Sashida G, Chiba T, Yuan J, Mochizuki-Kashio M, Suzuki Y, Sugano S, Nakaseko C, Yokote K, Koseki H, Iwama A. Tanaka S, et al. Blood. 2012 Aug 2;120(5):1107-17. doi: 10.1182/blood-2011-11-394932. Epub 2012 Jun 7. Blood. 2012. PMID: 22677129 Free article.

8

Compromised hematopoiesis and increased DNA damage following non-lethal ionizing radiation of a human hematopoietic system reconstituted in immunodeficient mice.

Wang C, Nakamura S, Oshima M, Mochizuki-Kashio M, Nakajima-Takagi Y, Osawa M, Kusunoki Y, Kyoizumi S, Imai K, Nakachi K, Iwama A. Wang C, et al. Int J Radiat Biol. 2013 Feb;89(2):132-7. doi: 10.3109/09553002.2013.734947. Epub 2012 Oct 25. Int J Radiat Biol. 2013. PMID: 23020858

9

Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.

Muto T, Sashida G, Oshima M, Wendt GR, Mochizuki-Kashio M, Nagata Y, Sanada M, Miyagi S, Saraya A, Kamio A, Nagae G, Nakaseko C, Yokote K, Shimoda K, Koseki H, Suzuki Y, Sugano S, Aburatani H, Ogawa S, Iwama A. Muto T, et al. J Exp Med. 2013 Nov 18;210(12):2627-39. doi: 10.1084/jem.20131144. Epub 2013 Nov 11. J Exp Med. 2013. PMID: 24218139 Free PMC article.

10

The TIF1β-HP1 system maintains transcriptional integrity of hematopoietic stem cells.

Miyagi S, Koide S, Saraya A, Wendt GR, Oshima M, Konuma T, Yamazaki S, Mochizuki-Kashio M, Nakajima-Takagi Y, Wang C, Chiba T, Kitabayashi I, Nakauchi H, Iwama A. Miyagi S, et al. Stem Cell Reports. 2014 Jan 23;2(2):145-52. doi: 10.1016/j.stemcr.2013.12.008. eCollection 2014 Feb 11. Stem Cell Reports. 2014. PMID: 24527388 Free PMC article.

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