Modena D - Search Results

1

The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo.

Leoni F, Fossati G, Lewis EC, Lee JK, Porro G, Pagani P, Modena D, Moras ML, Pozzi P, Reznikov LL, Siegmund B, Fantuzzi G, Dinarello CA, Mascagni P. Leoni F, et al. Among authors: modena d. Mol Med. 2005 Jan-Dec;11(1-12):1-15. doi: 10.2119/2006-00005.Dinarello. Mol Med. 2005. PMID: 16557334 Free PMC article.

2

Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat).

Furlan A, Monzani V, Reznikov LL, Leoni F, Fossati G, Modena D, Mascagni P, Dinarello CA. Furlan A, et al. Among authors: modena d. Mol Med. 2011 May-Jun;17(5-6):353-62. doi: 10.2119/molmed.2011.00020. Epub 2011 Feb 22. Mol Med. 2011. PMID: 21365126 Free PMC article. Clinical Trial.

3

Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivo.

Li S, Fossati G, Marchetti C, Modena D, Pozzi P, Reznikov LL, Moras ML, Azam T, Abbate A, Mascagni P, Dinarello CA. Li S, et al. Among authors: modena d. J Biol Chem. 2015 Jan 23;290(4):2368-78. doi: 10.1074/jbc.M114.618454. Epub 2014 Dec 1. J Biol Chem. 2015. PMID: 25451941 Free PMC article.

4

ITF1697, a stable Lys-Pro-containing peptide, inhibits weibel-palade body exocytosis induced by ischemia/reperfusion and pressure elevation.

Bertuglia S, Ichimura H, Fossati G, Parthasarathi K, Leoni F, Modena D, Cremonesi P, Bhattacharya J, Mascagni P. Bertuglia S, et al. Among authors: modena d. Mol Med. 2007 Nov-Dec;13(11-12):615-24. doi: 10.2119/2007-00079.Bertuglia. Mol Med. 2007. PMID: 17948065 Free PMC article.

5

Novel Benzohydroxamate-Based Potent and Selective Histone Deacetylase 6 (HDAC6) Inhibitors Bearing a Pentaheterocyclic Scaffold: Design, Synthesis, and Biological Evaluation.

Vergani B, Sandrone G, Marchini M, Ripamonti C, Cellupica E, Galbiati E, Caprini G, Pavich G, Porro G, Rocchio I, Lattanzio M, Pezzuto M, Skorupska M, Cordella P, Pagani P, Pozzi P, Pomarico R, Modena D, Leoni F, Perego R, Fossati G, Steinkühler C, Stevenazzi A. Vergani B, et al. Among authors: modena d. J Med Chem. 2019 Dec 12;62(23):10711-10739. doi: 10.1021/acs.jmedchem.9b01194. Epub 2019 Nov 25. J Med Chem. 2019. PMID: 31710483

6

Diaminic carbonates, a new class of anti-inflammatory compounds: their biological characterization and mode of action.

Porro G, Bertolini G, Bonardi MA, Giovanetti E, Lento P, Leoni F, Modena D, Pavich G, Marcucci F. Porro G, et al. Among authors: modena d. J Pharmacol Exp Ther. 1998 Apr;285(1):193-200. J Pharmacol Exp Ther. 1998. PMID: 9536010

7

Modulation of gamma globin genes expression by histone deacetylase inhibitors: an in vitro study.

Ronzoni L, Sonzogni L, Fossati G, Modena D, Trombetta E, Porretti L, Cappellini MD. Ronzoni L, et al. Among authors: modena d. Br J Haematol. 2014 Jun;165(5):714-21. doi: 10.1111/bjh.12814. Epub 2014 Mar 7. Br J Haematol. 2014. PMID: 24606390 Free article.

8

Preventive administration of Mycobacterium tuberculosis 10-kDa heat shock protein (hsp10) suppresses adjuvant arthritis in Lewis rats.

Agnello D, Scanziani E, Di GM, Leoni F, Modena D, Mascagni P, Introna M, Ghezzi P, Villa P. Agnello D, et al. Among authors: modena d. Int Immunopharmacol. 2002 Mar;2(4):463-74. doi: 10.1016/s1567-5769(01)00188-6. Int Immunopharmacol. 2002. PMID: 11962726

9

Cochaperonins are histone-binding proteins.

Bonardi MA, Giovanetti E, Legname G, Fossati G, Porro G, Gromo G, Modena D, Marcucci F. Bonardi MA, et al. Among authors: modena d. Biochem Biophys Res Commun. 1995 Jan 5;206(1):260-5. doi: 10.1006/bbrc.1995.1036. Biochem Biophys Res Commun. 1995. PMID: 7818529

10

Evidence for GroES acting as a transcriptional regulator.

Legname G, Buono P, Fossati G, Monzini N, Mascagni P, Modena D, Marcucci F. Legname G, et al. Among authors: modena d. Biochem Biophys Res Commun. 1996 Dec 13;229(2):412-8. doi: 10.1006/bbrc.1996.1818. Biochem Biophys Res Commun. 1996. PMID: 8954912

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