Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease.
Kadyrov FA, Holmes SF, Arana ME, Lukianova OA, O'Donnell M, Kunkel TA, Modrich P.
Kadyrov FA, et al. Among authors: modrich p.
J Biol Chem. 2007 Dec 21;282(51):37181-90. doi: 10.1074/jbc.M707617200. Epub 2007 Oct 19.
J Biol Chem. 2007.
PMID: 17951253
Free PMC article.
Human MutLalpha (MLH1-PMS2 heterodimer) harbors a latent endonuclease that is dependent on the integrity of a PMS2 DQHA(X)2E(X)4E motif (Kadyrov, F. A., Dzantiev, L., Constantin, N., and Modrich, P. (2006) Cell 126, 297-308). This sequence element is conserved in ma …
Human MutLalpha (MLH1-PMS2 heterodimer) harbors a latent endonuclease that is dependent on the integrity of a PMS2 DQHA(X)2E(X)4E motif (Kad …