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Modulation of innate and adaptive immunity by P2X ion channels.
Di Virgilio F, Sarti AC, Grassi F. Di Virgilio F, et al. Curr Opin Immunol. 2018 Jun;52:51-59. doi: 10.1016/j.coi.2018.03.026. Epub 2018 Apr 7. Curr Opin Immunol. 2018. PMID: 29631184 Review.
In the inflammatory microenvironment ATP binds and activates nucleotide receptors of the P2Y and P2X subfamilies expressed by immune cells. P2Y receptors are G-protein-coupled, while P2X receptors are cation-selective channels. Changes in the intracellular …
In the inflammatory microenvironment ATP binds and activates nucleotide receptors of the P2Y and P2X subfamilies expressed by immune …
IL-27 enhances LPS-induced IL-1β in human monocytes and murine macrophages.
Petes C, Wynick C, Guzzo C, Mehta D, Logan S, Banfield BW, Basta S, Cooper A, Gee K. Petes C, et al. J Leukoc Biol. 2017 Jul;102(1):83-94. doi: 10.1189/jlb.3A0316-098R. Epub 2017 Apr 4. J Leukoc Biol. 2017. PMID: 28377398 Free PMC article.
IL-27 bridges innate and adaptive immunity by modulating cytokine production from myeloid cells and regulating Th cell differentiation. ...Herein, we investigated the molecular mechanisms by which IL-27 modulates LPS-induced IL-1beta secretion i …
IL-27 bridges innate and adaptive immunity by modulating cytokine production from myeloid cells and regulating T …