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The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation.
Poulsen ET, Nielsen NS, Scavenius C, Mogensen EH, Risør MW, Runager K, Lukassen MV, Rasmussen CB, Christiansen G, Richner M, Vorum H, Enghild JJ. Poulsen ET, et al. Among authors: mogensen eh. J Biol Chem. 2019 Aug 2;294(31):11817-11828. doi: 10.1074/jbc.RA119.009050. Epub 2019 Jun 13. J Biol Chem. 2019. PMID: 31197037 Free PMC article.
Biochemical mechanisms of aggregation in TGFBI-linked corneal dystrophies.
Nielsen NS, Poulsen ET, Lukassen MV, Chao Shern C, Mogensen EH, Weberskov CE, DeDionisio L, Schauser L, Moore TCB, Otzen DE, Hjortdal J, Enghild JJ. Nielsen NS, et al. Among authors: mogensen eh. Prog Retin Eye Res. 2020 Jul;77:100843. doi: 10.1016/j.preteyeres.2020.100843. Epub 2020 Jan 29. Prog Retin Eye Res. 2020. PMID: 32004730 Review.
A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage.
Yamamoto K, Scavenius C, Meschis MM, Gremida AME, Mogensen EH, Thøgersen IB, Bonelli S, Scilabra SD, Jensen A, Santamaria S, Ahnström J, Bou-Gharios G, Enghild JJ, Nagase H. Yamamoto K, et al. Among authors: mogensen eh. Matrix Biol. 2022 Sep;112:190-218. doi: 10.1016/j.matbio.2022.08.007. Epub 2022 Aug 24. Matrix Biol. 2022. PMID: 36028175 Free article.