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A New Molecular Mechanism To Engineer Protean Agonism at a G Protein-Coupled Receptor.
De Min A, Matera C, Bock A, Holze J, Kloeckner J, Muth M, Traenkle C, De Amici M, Kenakin T, Holzgrabe U, Dallanoce C, Kostenis E, Mohr K, Schrage R. De Min A, et al. Mol Pharmacol. 2017 Apr;91(4):348-356. doi: 10.1124/mol.116.107276. Epub 2017 Feb 6. Mol Pharmacol. 2017. PMID: 28167741
Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist.
Grossmüller M, Antony J, Tränkle C, Holzgrabe U, Mohr K. Grossmüller M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2006 Jan;372(4):267-76. doi: 10.1007/s00210-005-0023-4. Epub 2005 Dec 16. Naunyn Schmiedebergs Arch Pharmacol. 2006. PMID: 16362429
A muscarinic view on Gq.
Mohr K, Tränkle C. Mohr K, et al. Naunyn Schmiedebergs Arch Pharmacol. 2013 Nov;386(11):935-6. doi: 10.1007/s00210-013-0895-7. Naunyn Schmiedebergs Arch Pharmacol. 2013. PMID: 23779215 No abstract available.
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