Mohr K - Search Results

1

Two-point kinetic experiments to quantify allosteric effects on radioligand dissociation.

Kostenis E, Mohr K. Kostenis E, et al. Among authors: mohr k. Trends Pharmacol Sci. 1996 Aug;17(8):280-3. doi: 10.1016/0165-6147(96)10034-1. Trends Pharmacol Sci. 1996. PMID: 8810873 Review.

2

Hexamethonium-type allosteric modulators of the muscarinic receptors bearing lateral dibenzazepine moieties.

Li R, Tränkle C, Mohr K, Holzgrabe U. Li R, et al. Among authors: mohr k. Arch Pharm (Weinheim). 2001 Apr;334(4):121-4. doi: 10.1002/1521-4184(200104)334:4<121::aid-ardp121>3.0.co;2-t. Arch Pharm (Weinheim). 2001. PMID: 11382147

3

Evidence for a multiple binding mode of bispyridinium-type allosteric modulators of muscarinic receptors.

Kostenis E, Botero Cid HM, Holzgrabe Y, Mohr K. Kostenis E, et al. Among authors: mohr k. Eur J Pharmacol. 1996 Oct 31;314(3):385-92. doi: 10.1016/s0014-2999(96)00568-7. Eur J Pharmacol. 1996. PMID: 8957263

4

Bisquaternary ligands of the common allosteric site of M2 acetylcholine receptors: search for the minimum essential distances between the pharmacophoric elements.

Nassif-Makki T, Tränkle C, Zlotos D, Bejeuhr G, Cambareri A, Pfletschinger C, Kostenis E, Mohr K, Holzgrabe U. Nassif-Makki T, et al. Among authors: mohr k. J Med Chem. 1999 Mar 11;42(5):849-58. doi: 10.1021/jm981023f. J Med Chem. 1999. PMID: 10072682

5

Contribution of lateral substituents in heptane-bisammonium derivatives to the allosteric stabilization of antagonist binding to M2-receptors.

Staudt M, Tränkle C, Mohr K, Holzgrabe U. Staudt M, et al. Among authors: mohr k. Life Sci. 1998;62(5):423-9. doi: 10.1016/s0024-3205(97)01135-1. Life Sci. 1998. PMID: 9449232

6

Molecular rigidity and potency of bispyridinium type allosteric modulators at muscarinic M2-receptors.

Tränkle C, Elis K, Wiese M, Mohr K. Tränkle C, et al. Among authors: mohr k. Life Sci. 1997;60(22):1995-2003. doi: 10.1016/s0024-3205(97)00164-1. Life Sci. 1997. PMID: 9180353

7

Probing the size of a hydrophobic binding pocket within the allosteric site of muscarinic acetylcholine M2-receptors.

Bender W, Staudt M, Tränkle C, Mohr K, Holzgrabe U. Bender W, et al. Among authors: mohr k. Life Sci. 2000 Mar 24;66(18):1675-82. doi: 10.1016/s0024-3205(00)00490-2. Life Sci. 2000. PMID: 10809164

8

Muscarinic allosteric modulators: atypical structure-activity-relationships in bispyridinium-type compounds.

Sürig U, Gaal K, Kostenis E, Tränkle C, Mohr K, Holzgrabe U. Sürig U, et al. Among authors: mohr k. Arch Pharm (Weinheim). 2006 Apr;339(4):207-12. doi: 10.1002/ardp.200600005. Arch Pharm (Weinheim). 2006. PMID: 16572483

9

Systematic development of high affinity bis(ammonio)alkane-type allosteric enhancers of muscarinic ligand binding.

Muth M, Bender W, Scharfenstein O, Holzgrabe U, Balatkova E, Tränkle C, Mohr K. Muth M, et al. Among authors: mohr k. J Med Chem. 2003 Mar 13;46(6):1031-40. doi: 10.1021/jm021017q. J Med Chem. 2003. PMID: 12620079

10

Development of a new type of allosteric modulator of muscarinic receptors: hybrids of the antagonist AF-DX 384 and the hexamethonio derivative W84.

Mohr M, Heller E, Ataie A, Mohr K, Holzgrabe U. Mohr M, et al. Among authors: mohr k. J Med Chem. 2004 Jun 3;47(12):3324-7. doi: 10.1021/jm031095t. J Med Chem. 2004. PMID: 15163212

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