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Edwardsiella tarda - virulence mechanisms of an emerging gastroenteritis pathogen.
Leung KY, Siame BA, Tenkink BJ, Noort RJ, Mok YK. Leung KY, et al. Among authors: mok yk. Microbes Infect. 2012 Jan;14(1):26-34. doi: 10.1016/j.micinf.2011.08.005. Epub 2011 Sep 1. Microbes Infect. 2012. PMID: 21924375 Review.
Two-component PhoB-PhoR regulatory system and ferric uptake regulator sense phosphate and iron to control virulence genes in type III and VI secretion systems of Edwardsiella tarda.
Chakraborty S, Sivaraman J, Leung KY, Mok YK. Chakraborty S, et al. Among authors: mok yk. J Biol Chem. 2011 Nov 11;286(45):39417-30. doi: 10.1074/jbc.M111.295188. Epub 2011 Sep 27. J Biol Chem. 2011. PMID: 21953460 Free PMC article.
Type VI secretion regulation: crosstalk and intracellular communication.
Leung KY, Siame BA, Snowball H, Mok YK. Leung KY, et al. Among authors: mok yk. Curr Opin Microbiol. 2011 Feb;14(1):9-15. doi: 10.1016/j.mib.2010.09.017. Curr Opin Microbiol. 2011. PMID: 20971679 Review.
A disordered region in the EvpP protein from the type VI secretion system of Edwardsiella tarda is essential for EvpC binding.
Hu W, Anand G, Sivaraman J, Leung KY, Mok YK. Hu W, et al. Among authors: mok yk. PLoS One. 2014 Nov 17;9(11):e110810. doi: 10.1371/journal.pone.0110810. eCollection 2014. PLoS One. 2014. PMID: 25401506 Free PMC article.
Temperature and Mg2+ sensing by a novel PhoP-PhoQ two-component system for regulation of virulence in Edwardsiella tarda.
Chakraborty S, Li M, Chatterjee C, Sivaraman J, Leung KY, Mok YK. Chakraborty S, et al. Among authors: mok yk. J Biol Chem. 2010 Dec 10;285(50):38876-88. doi: 10.1074/jbc.M110.179150. Epub 2010 Oct 11. J Biol Chem. 2010. PMID: 20937832 Free PMC article.
Structural basis for the secretion of EvpC: a key type VI secretion system protein from Edwardsiella tarda.
Jobichen C, Chakraborty S, Li M, Zheng J, Joseph L, Mok YK, Leung KY, Sivaraman J. Jobichen C, et al. Among authors: mok yk. PLoS One. 2010 Sep 23;5(9):e12910. doi: 10.1371/journal.pone.0012910. PLoS One. 2010. PMID: 20886112 Free PMC article.
EseG, an effector of the type III secretion system of Edwardsiella tarda, triggers microtubule destabilization.
Xie HX, Yu HB, Zheng J, Nie P, Foster LJ, Mok YK, Finlay BB, Leung KY. Xie HX, et al. Among authors: mok yk. Infect Immun. 2010 Dec;78(12):5011-21. doi: 10.1128/IAI.00152-10. Epub 2010 Sep 20. Infect Immun. 2010. PMID: 20855515 Free PMC article.
EscC is a chaperone for the Edwardsiella tarda type III secretion system putative translocon components EseB and EseD.
Zheng J, Li N, Tan YP, Sivaraman J, Mok YK, Mo ZL, Leung KY. Zheng J, et al. Among authors: mok yk. Microbiology (Reading). 2007 Jun;153(Pt 6):1953-1962. doi: 10.1099/mic.0.2006/004952-0. Microbiology (Reading). 2007. PMID: 17526852
Structure of AcrH-AopB Chaperone-Translocator Complex Reveals a Role for Membrane Hairpins in Type III Secretion System Translocon Assembly.
Nguyen VS, Jobichen C, Tan KW, Tan YW, Chan SL, Ramesh K, Yuan Y, Hong Y, Seetharaman J, Leung KY, Sivaraman J, Mok YK. Nguyen VS, et al. Among authors: mok yk. Structure. 2015 Nov 3;23(11):2022-31. doi: 10.1016/j.str.2015.08.014. Epub 2015 Oct 1. Structure. 2015. PMID: 26439768
Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-κB p50.
Nguyen VS, Loh XY, Wijaya H, Wang J, Lin Q, Lam Y, Wong WS, Mok YK. Nguyen VS, et al. Among authors: mok yk. J Nat Prod. 2015 Feb 27;78(2):208-17. doi: 10.1021/np5007179. Epub 2015 Jan 23. J Nat Prod. 2015. PMID: 25615020
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