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Page 1
Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles.
Billmann M, Costanzo M, Zhang X, Hassan AZ, Rahman M, Brown KR, Chan KS, Tong AHY, Pons C, Ward HN, Ross C, van Leeuwen J, Aregger M, Lawson KA, Mair B, Roth AF, Sen NE, Forster DT, Tan G, Mero P, Masud SN, Lee Y, Aguilera-Uribe M, Ušaj M, Almeida SMT, Aulakh K, Bhojoo U, Birkadze S, Budijono N, Cai X, Caumanns JJ, Chalmers JJ, Chandrashekhar M, Chang D, Climie R, Dasgupta K, Drazic A, Echenique JIR, Gacesa R, Farias AG, Habsid A, Horecka I, Kantautas K, Ji F, Kim DK, Lee SY, Liang W, Lim HJ, Lin K, Lu X, Maier M, Nami B, Nixon A, Mikolajewicz N, Mokhtaridoost M, Nedyalkova L, Rohde T, Rodrigues MS, Soste M, Schultz E, Wang W, Seetharaman A, Shuteriqi E, Sizova O, Taylor DT, Tereshchenko M, Tieu D, Turowec J, Ubhi T, Varland S, Wang KE, Wang ZY, Wei J, Xiao YX, Maass PG, Reversade B, Brown GW, Cravatt BF, Dixon SJ, Wyatt HDM, Röst HL, Roth FP, Xia T, Bader GD, Loewith R, Davis NG, Andrews B, Myers CL, Moffat J, Boone C. Billmann M, et al. Among authors: mokhtaridoost m. Cell. 2026 Apr 27:S0092-8674(26)00345-4. doi: 10.1016/j.cell.2026.03.044. Online ahead of print. Cell. 2026. PMID: 42049019 Free article.
LncRNA CISTR-ACT regulates cell size in human and mouse by guiding FOSL2.
Kiriakopulos K, Soleimanpour K, McMurray BJ, Moke BI, Chalmers JJ, Mokhtaridoost M, Newton JD, De Young T, Delfosse K, Ahmed M, Wong CJ, Stricker S, Li Y, Nieman BJ, Gingras AC, Justice MJ, Lefebvre JL, Maass PG. Kiriakopulos K, et al. Among authors: mokhtaridoost m. Nat Commun. 2025 Dec 16;17(1):872. doi: 10.1038/s41467-025-67591-x. Nat Commun. 2025. PMID: 41397992 Free PMC article.
tRNA-overlapping long non-coding RNA loci repress codon-biased genes.
Ahmed S, Fine JL, Chalmers JJ, Kiriakopulos K, Clarke LA, Suárez CC, Soleimanpour K, Oliveros W, Delfosse K, Mokhtaridoost M, Wong CJ, Gingras AC, Ciruna B, Fabian MR, Blencowe BJ, Maass PG. Ahmed S, et al. Among authors: mokhtaridoost m. Cell Rep. 2025 Oct 28;44(10):116417. doi: 10.1016/j.celrep.2025.116417. Epub 2025 Oct 9. Cell Rep. 2025. PMID: 41075247 Free article.
Inter-chromosomal contacts demarcate genome topology along a spatial gradient.
Mokhtaridoost M, Chalmers JJ, Soleimanpoor M, McMurray BJ, Lato DF, Nguyen SC, Musienko V, Nash JO, Espeso-Gil S, Ahmed S, Delfosse K, Browning JWL, Barutcu AR, Wilson MD, Liehr T, Shlien A, Aref S, Joyce EF, Weise A, Maass PG. Mokhtaridoost M, et al. Nat Commun. 2024 Nov 13;15(1):9813. doi: 10.1038/s41467-024-53983-y. Nat Commun. 2024. PMID: 39532865 Free PMC article.
Systematic characterization of regulatory variants of blood pressure genes.
Oliveros W, Delfosse K, Lato DF, Kiriakopulos K, Mokhtaridoost M, Said A, McMurray BJ, Browning JWL, Mattioli K, Meng G, Ellis J, Mital S, Melé M, Maass PG. Oliveros W, et al. Among authors: mokhtaridoost m. Cell Genom. 2023 May 24;3(7):100330. doi: 10.1016/j.xgen.2023.100330. eCollection 2023 Jul 12. Cell Genom. 2023. PMID: 37492106 Free PMC article.